Antibiotics 2

Question 1

Viral infections do not respond to these

Answer 1

Antibiotics

Question 2

When to use antibiotics

Answer 2

1) Fever or chills within the last 24 hours.
2) Malaise, fatigue, weakness, dizziness, rapid respiration.
3) Trismus
4) Cellulitis
5) Local or systemic infection with a hx of rheumatic fever, endocarditits, heart prosthesis.
6) Immunocompromised status (AIDS, cancer, autoimmune diseases, corticosteroid therapy).
7) Allograph (cardiac, renal, bone marrow, liver, osseous implant).
8) Diabetes mellitus Type I, II , or III.

Question 3

A beta-lactam antibiotic

Answer 3

Penicillin G or V

Question 4

Only natural penicillin still in use, and has a short half-life.

Not used orally bc the half life is so short.

Answer 4

Pen G

Question 5

Acid stable penicillin that’s well absorbed orally.

Answer 5

Pen V

Question 6

The most widely prescribed antibiotic.

Answer 6

Amoxicillin

Question 7

Enzyme that breaks down the beta-lactam rings in some antibiotics.

Answer 7

Penicillinase

Question 8

Prevent the breakdown of beta lactam antibtiotics.

Answer 8

Beta-lactamase inhibitors

Question 9

A type of beta lactamase inhibitor.

Answer 9

Clavulanic acid

Question 10

Components of Augmentin.

Answer 10

Amoxicillin + Clavulanic acid

Question 11

Substitute for Penicillin

Answer 11

Cephalosporin

Question 12

The more advanced the generation of cephalosporins, the more ______ the spectrum.

Answer 12

Broad

Question 13

Bind to 30s ribosomal subunit to inhibit protein synthesis.

Answer 13

Tetracyclines

Question 14

Long action tetracycline.

Answer 14

Doxy and Minocycline

Question 15

Cause dental staining when given to kids under 12.

Answer 15

Tetracyclines.

Question 16

This antibiotic is used for:

• Orofacial infections
• Adjunct in treating periodontitis
• NUG
• Periodontal abscesses

Answer 16

Tetracyclines

Question 17

Tetracyclines bind to these cations, which are found in dairy products and antacids.

Answer 17

Ca2+
Mg 2+
Fe2+
Al3+

Question 18

Abs that bind to 50s ribosomal subunit to inhibit protein synthesis.

Answer 18

Macrolides (Erythromycin and Clindamycin).

Question 19

Not the drug of choice for anaerobic odontogenic infections.

Answer 19

Macrolides

Question 20

One of the most interactive (causes bad drug interactions) antibiotics that we have.

Answer 20

Erythromycin

Question 21

Has poor tissue concentration and is acid labile (destroyed by the acidic stomac).

Answer 21

Erythromycin

Question 22

Macrolide ab used for upper/lower respiratory infections, skin and soft tissue infections, and STD’s.

Answer 22

Azithromycin

Question 23

This ab is engulfed by phagocytes and transported to the site of infection.

Answer 23

Azithromycin

Question 24

Ab for people with kidney failure bc it’s metabolized thru the liver, not the kidney.

Answer 24

Clindamycin

Question 25

Ab that cannot be taken with alcohol.

Answer 25

Metronidazole

Question 26

Ab that’s a DNA gyrase inhibitor.

Answer 26

Quinolone