Antibiotics 1 Flashcards
Abs that affect cell wall synthesis.
Penicillin and Cephalosporin
Abs that affect protein synthesis.
Erythromycin and Clindamycin
Tetracyclines, Macrolides, Linomycins inhibit:
protein synthesis
Inhibit nucelic acid synthesis.
Nitroimidizoles
Quinolones
Tetracyclines are bacteriostatic or cidal?
STATIC
Clindamycin bacteriostatic or cidal?
Depends on the dose.
Low dose Clindamycin.
Bacteriostatic
High dose Clindamycin.
Bacteriocidal
Augmentin, Metronidazole, Amoxicillin bacterio static or cidal?
CIDAL
Tetracycline is what pregnancy risk category?
D
Clarithromycin and Ciprofloxin is what pregnancy category?
C
Tetracyclines are used for what perio therapy?
LAP, GAP, refractory cases
Augmentin is used for what perio therapy?
Refectory, LAP
Metronidazole is used for what perio therapy?
Severe adult cases
Amoxicillin + Metronidazole
or
Augmentin + Metronidazole
are used for what perio therapy?
LAP, GAP, refractory
Clidnamycin is used for what perio therapies?
LAP and refractory
Overgrowth of C. difficile is caused by which antiobiotic?
Clindamycin
Overgrowth of C. difficile is called what?
Pseudomembranous colitis
Most cases of pseudomembranous colitis are caused by which antibiotics?
Cephalosporins
Clindamycin is what pregnancy category?
B
Clindamycin has high or low protein binding?
High
So it’s widely distributed in the body,
Ab associated with wide distribution in bone.
Clindamycin
Therapy for a Failing Implant
1) Establish biofilm control by using an antiseptic mouthrinse and toothpaste.
2) Debridement
3) Local delivery of medication
4) Clindamycin systemic
5) Followed by low dose doxycycline
You get poor absorption of drugs in areas of high or low pH?
LOW
Like in an abscess- concentration of antibiotic is lower here.
