antibiotics

Question 1

synthetic antibacterials

Answer 1

FQ
Nitroimidazoles
oxazolidinones
trimethoprim
sulfonamides

Question 2

natural antibiotics

Answer 2

Penicillins
cephalosporins
carbapenems
monobactams
glycopeptides
lipopeptides
aminoglycosides
macrolides
lincomycins
streptogramins
tetracyclines

Question 3

Isoniazid

Answer 3

Mycobacteria

Inhibition of cell wall synthesis

Question 4

Aztreonam

Answer 4

Gram Negative

Question 5

Vancomycin

Answer 5

Gram Positive

Inhibition of cell wall synthesis

Question 6

Sulfonamides

Answer 6

Gram Negative and Positive

Question 7

Penicillin

Answer 7

Cidal Drugs
Gram Negative and Positive
Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

Question 8

Cephlosporins

Answer 8

Cidal Drugs
Gram Negative and Positive
Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

Question 9

Aminglycosides

Answer 9

Mycobacteria, Gram Negative and Positive

Inhibition of protein synthesis- Binds to 30s impaires translation of mRNA into protein

Question 10

Macrolides (Erythromycin, Azythromycin)

Answer 10

Static Drugs
Gram Positive, Chlamydias, Rikettsia, Mycoplasmas
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

Question 11

Tetracycline

Answer 11

Static Drugs
Gram Negative and Positive Chlamydias, Rikettsia, Mycoplasmas
Inhibition of protein synthesis- Binds to 30s impaires translation of mRNA into protein

Question 12

Fluoroquinolones

Answer 12

synthetic antibacterials
Cidal Drugs
Mycobacteria, Gram Negative and Positive Chlamydias, Rikettsia, Mycoplasmas
Inhibits DNA gyrase

Question 13

carbapenems

Answer 13

Cidal Drugs

Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

Question 14

Monobactams

Answer 14

Cidal Drugs

Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

Question 15

Bacitacin

Answer 15

Cidal Drugs

Inhibition of cell wall synthesis

Question 16

Lincosamides

Answer 16

Static Drugs
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

Question 17

chlormaphericol

Answer 17

Static Drugs
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

Question 18

streptogramins

Answer 18

Static Drugs
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

Question 19

Oxazolidionones

Answer 19

Static Drugs
synthetic antibacterials
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

Question 20

Nitroimidazoles

Answer 20

synthetic antibacterials

Short lived toxins cause DNA strand breakage, loss of conformation and impaired template function

Question 21

rifampin

Answer 21

Cidal Drugs

Short lived toxins cause DNA strand breakage, loss of conformation and impaired template function

Question 22

trimethoprim

Answer 22

synthetic antibacterials
Inhibit enzymes: dihydrofolate reductase
prevent folates from forming

Question 23

Sulfonamide

Answer 23

synthetic antibacterials
Inhibit enzymes: tetrahydropteroic acid synthetase
prevent folates from forming

Question 24

Polymyxins

Answer 24

Cidal Drugs
Disrupts structural integrity and ion flow through cytoplasmic membranes
Causes toxicity to host

Question 25

lipopeptides

Answer 25

Cidal Drugs Disrupts structural integrity and ion flow through cytoplasmic membranes Causes toxicity to host

Question 26

Static Drugs

Answer 26

``` Any drug that targets a ribosome, or protein synthesis Exception is AG (cidal) even though they target ribosomes Tetracyclines Macrolides/Ketolides Lincosamides Chloramphenicol Streptogramins Oxazolindinones ```

Question 27

Cidal Drugs

Answer 27

``` AG Beta lactams Vancomycin Bacitracin Isoniazid Fosfomycin FQ Metronidazole Rifampin Polymyxins Lipopeptides ```

Question 28

targets for antibiotics

Answer 28

Cell wall Inner cell membrane Ribosomes and protein synthesis Nucleic acids and folates

Question 29

Viruses that can be treated with drugs and Vaccines

Answer 29

Influenza chronic Hep B Genital warts chicken pox/ shingles

Question 30

Viruses that can be treated with drugs

Answer 30

Hep C HIV/AIDS Respiratory illness in infants Herpes