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Bugs and drugs- Test 1 > antibiotics > Flashcards

antibiotics Flashcards

1
Q

synthetic antibacterials

A 
FQ
Nitroimidazoles
oxazolidinones
trimethoprim
sulfonamides
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2
Q

natural antibiotics

A 
Penicillins
cephalosporins
carbapenems
monobactams
glycopeptides
lipopeptides
aminoglycosides
macrolides
lincomycins
streptogramins
tetracyclines
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3
Q

Isoniazid

A

Mycobacteria

Inhibition of cell wall synthesis

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4
Q

Aztreonam

A

Gram Negative

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5
Q

Vancomycin

A

Gram Positive

Inhibition of cell wall synthesis

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6
Q

Sulfonamides

A

Gram Negative and Positive

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7
Q

Penicillin

A

Cidal Drugs
Gram Negative and Positive
Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

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8
Q

Cephlosporins

A

Cidal Drugs
Gram Negative and Positive
Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

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9
Q

Aminglycosides

A

Mycobacteria, Gram Negative and Positive

Inhibition of protein synthesis- Binds to 30s impaires translation of mRNA into protein

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10
Q

Macrolides (Erythromycin, Azythromycin)

A

Static Drugs
Gram Positive, Chlamydias, Rikettsia, Mycoplasmas
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

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11
Q

Tetracycline

A

Static Drugs
Gram Negative and Positive Chlamydias, Rikettsia, Mycoplasmas
Inhibition of protein synthesis- Binds to 30s impaires translation of mRNA into protein

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12
Q

Fluoroquinolones

A

synthetic antibacterials
Cidal Drugs
Mycobacteria, Gram Negative and Positive Chlamydias, Rikettsia, Mycoplasmas
Inhibits DNA gyrase

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13
Q

carbapenems

A

Cidal Drugs

Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

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14
Q

Monobactams

A

Cidal Drugs

Inhibition of cell wall synthesis (mostly cidal)- produce beta lactams

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15
Q

Bacitacin

A

Cidal Drugs

Inhibition of cell wall synthesis

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16
Q

Lincosamides

A

Static Drugs
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

17
Q

chlormaphericol

A

Static Drugs
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

18
Q

streptogramins

A

Static Drugs
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

19
Q

Oxazolidionones

A

Static Drugs
synthetic antibacterials
Inhibition of protein synthesis- Binds to 50s causes blockage of transpeptidation or translocation reactions interfering with translation of mRNA into protein

20
Q

Nitroimidazoles

A

synthetic antibacterials

Short lived toxins cause DNA strand breakage, loss of conformation and impaired template function

21
Q

rifampin

A

Cidal Drugs

Short lived toxins cause DNA strand breakage, loss of conformation and impaired template function

22
Q

trimethoprim

A

synthetic antibacterials
Inhibit enzymes: dihydrofolate reductase
prevent folates from forming

23
Q

Sulfonamide

A

synthetic antibacterials
Inhibit enzymes: tetrahydropteroic acid synthetase
prevent folates from forming

24
Q

Polymyxins

A

Cidal Drugs
Disrupts structural integrity and ion flow through cytoplasmic membranes
Causes toxicity to host

25
Q

lipopeptides

A

Cidal Drugs
Disrupts structural integrity and ion flow through cytoplasmic membranes
Causes toxicity to host

26
Q

Static Drugs

A 
Any drug that targets a ribosome, or protein synthesis
Exception is AG (cidal) even though they target ribosomes
Tetracyclines
Macrolides/Ketolides
Lincosamides
Chloramphenicol
Streptogramins
Oxazolindinones
27
Q

Cidal Drugs

A 
AG
Beta lactams
Vancomycin
Bacitracin
Isoniazid
Fosfomycin
FQ
Metronidazole
Rifampin
Polymyxins
Lipopeptides
28
Q

targets for antibiotics

A

Cell wall
Inner cell membrane
Ribosomes and protein synthesis
Nucleic acids and folates

29
Q

Viruses that can be treated with drugs and Vaccines

A

Influenza
chronic Hep B
Genital warts
chicken pox/ shingles

30
Q

Viruses that can be treated with drugs

A

Hep C
HIV/AIDS
Respiratory illness in infants
Herpes

Bugs and drugs- Test 1 (7 decks)

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