Antibiotics

Question 1

Target cell wall

Answer 1

penicillins
cephalosporins
glycopeptides

Question 2

glycopeptide mechanism of action

Answer 2

target cell wall side chains

Question 3

what gram stain of bacteria do glycopeptides work on?

Answer 3

gram pos

Question 4

penicillins mechanism of action

Answer 4

B-lactam ring
binds to PBP
prevents formation of peptidoglycan layers

Question 5

gram +/- penicillin?

Answer 5

amox

Question 6

what make up co-amoxiclav

Answer 6

amoxicillin
cluvulanic acid

Question 7

beta-lactamase resistance?

Answer 7

co-amoxiclav
tazobactam

Question 8

gram - coliform?

Answer 8

temocilin

Question 9

staph and strep only?

Answer 9

fluclox

Question 10

cephalosporin mechanism of action

Answer 10

Beta-lactam ring

Question 11

ceftriaxone?

Answer 11

cephalosporin

Question 12

vancomycin?

Answer 12

glycopeptide

Question 13

teicoplanin?

Answer 13

glycopeptide

Question 14

contraindiaction of glycopeptide?

Answer 14

kidney damage

Question 15

target prokaryotic nucleic acid

Answer 15

fluroquinolones
trimethoprim
metronidazole

Question 16

mechanism of action for quinolones

Answer 16

inhibit DNA synthesis
prevent DNA supercoiling

Question 17

cover of quinolones?

Answer 17

gram -
few +

Question 18

ciprofloxacin?

Answer 18

fluroquinolones

Question 19

causes tendonitis?

Answer 19

fluroquinolones

Question 20

inhibits folic acid synthesis?

Answer 20

trimethoprim

Question 21

used to treat UTI

Answer 21

trimethoprim

Question 22

metronidazole mechanism of action?

Answer 22

inhibits prokaryotic nucleic acid

Question 23

anaerobic cover?

Answer 23

metronidazole

Question 24

protazoa cover?

Answer 24

metronidazole

Question 25

protein synthesis inhibitors?

Answer 25

teracyclines macrolides aminoglycosides

Question 26

bind to 30s and stops protein chain elongation

Answer 26

tetracyclines

Question 27

deoxycycline?

Answer 27

tetracycline

Question 28

minocycline?

Answer 28

tetracycline

Question 29

restricted use in infants?

Answer 29

tetracyclines

Question 30

binds to 50s subunit interfere with protein synthesis

Answer 30

macrolides

Question 31

gram - macrolides

Answer 31

erythromycin clarithromycin

Question 32

gram + macrolide?

Answer 32

azythromycin

Question 33

which macrolide is safe in pregnancy?

Answer 33

erythromycin

Question 34

binds to aminoacyl site of 16s within 30s causes misread of genetic code

Answer 34

aminoglycosides

Question 35

gentamicin?

Answer 35

aminoglycoside

Question 36

gram - coliforms?

Answer 36

gentamicin

Question 37

is gent cidal or static?

Answer 37

bactericidal

Question 38

how is gent administered?

Answer 38

IV

Question 39

side effects of gent?

Answer 39

nephrotoxic CN8 damage

Question 40

Abe causing aplastic anemia

Answer 40

chloramphenicol

Question 41

tendon rupture

Answer 41

ciprofloxacin

Question 42

treat typhoid fever

Answer 42

chloramphenicol

Question 43

mechanism of action for chloramphenicol

Answer 43

bind to 50s subunit inhibit peptide transferase

Question 44

clindamycin mechanism

Answer 44

inhibits protein synthesis bind to 50s ribosome

Question 45

inhibit DNA gyrase

Answer 45

quinolones

Question 46

inhibit folate synthesis

Answer 46

trimethoprim sulphonamide

Question 47

causing photosensitive rash

Answer 47

tetracyclines

Question 48

dihydrofolate reductase inhibitor

Answer 48

trimethoprim

Question 49

amantadine

Answer 49

antiviral inhibit M2 uncoating

Question 50

sulphonamide

Answer 50

inhibits folic acid synthesis