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Core Conditions > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Chronic bronchitis common organisms

A

H. Influenza, moraxella, S. pneumoniae

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2
Q

Chronic bronchitis antibiotics

A

Amoxicillin/ clarithromycin

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3
Q

Uncomplicated community aquired pneumonia organisms

A

H.influenza, S.pneumoniae

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4
Q

Uncomplicated community aquired pneumonia antibiotics

A

Amoxicillin/ doxycycline/ clarithromycin

Staph suspect: flucloxacillin

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5
Q

Pneumonia due to atypical agents organisms

A

Chlamydia pneumoniae, Mycoplasma

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6
Q

Pneumonia due to atypical agents antibitoics

A

Clarithromycin

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7
Q

Hospital aquired pneumonia organisms

A

Pseudomonas, klebsiella, MRSA

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8
Q

Hospital aquired pneumonia antibiotics

A

<5d: co-amoxicav, cefuroxime

>5d: piptazo, Ceptazidime, Ciprofloxacin, Vancomycin

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9
Q

Urinary tract infections organisms

A

E.coli (70-95%)
Klebsiella
S.saprophyticus
Proteus

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10
Q

Uncomplicated lower UTI antibiotics

A

Sulfamethoxazole + trimethoprim

Nitrofurantoin

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11
Q

Uncomplicated pyelonephritis antibiotcs

A

Ciprofloxacin

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12
Q

Impetigo organisms

A

S. Pyogenes, S. Aureus

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13
Q

Cellulitis organisms

A

S.pyogenes, S.aureus

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14
Q

Impeitgo antibiotics

A

Tooical fusidic acid, flucloxacillin, erythomycin

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15
Q

Cellulitis antibitoics

A

Flucoxacillin, clarythomycin, erythromycin, doxycyline

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16
Q

Erysipelas organisms

A

Group A strep

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17
Q

Erysipelas antibiotics

A

Flucloxacillin, clarythromycin, erythromycin, doxycycline

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18
Q

Throat infection organism

A

Mostly S.pyogenes

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19
Q

Throat infection antibiotics

A

Phenoxymethyl penicillin, erythromycin

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20
Q

Sinusitis organisms

A

S. Pneumoniae, H.influenza, moraxella, S.Pyogenes

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21
Q

Sinusitis antibiotics

A

Amoxicillin, erythomycin, doxycycline

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22
Q

Otitis media organisms

A

S.pneumoniae, H.influenza, Moraxella

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23
Q

Otitis media antibiotics

A

Amoxicillin, erythromycin

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24
Q

Otitis externa organisms

A

P.aeruginosa, s.aureus

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25
Q

Otitis externa antibiotics

A

Flucoxacillin, erythromycin

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26
Q

Gonorrhea antibiotics

A

IM Ceftriaxone, Oral Azithromycin

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27
Q

Chlamydia antibiotics

A

Doxycycline, azithromycin

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28
Q

Syphillis antibiotics

A

Benzathine Benzylpenicillin, Doxycycline, Erythomycin

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29
Q

Bacterial vaginosis antibitoics

A

Metronidazole, topical clindamycin

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30
Q

PID antibiotics

A

Oral Ofloxacin + oral metronidazole, or IM Ceftriaxone + Oral Doxycycline + Oral Metronidazole

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31
Q

C. Diff or Clostridium Difficile antibiotics

A

Metronidazole (if mild and first instance)

Vancomycin

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32
Q

Campylobacter antibiotics

A

Clarithromycin

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33
Q

Non-thyphoid salmonella

A

Ciprofloxacin

34
Q

Bacterial meningitid organisms

A

S.Pneumoniae, N.meningitidis, H.influenza, MRSA

35
Q

Bacterial meningitis antibiotics

A

Ceftriaxone, vancomycin, linezolid, ciprofloxacin, meropenem

36
Q

Examples of aminoglycosides

A

Streptamycin, gentamycin,

37
Q

Aminoglycoside mechanisms

A

Inhibit protein synthesis (bind 30s Ribosomal subunit)

38
Q

Aminoglycosides cover

A

Gram negative + gram positive

Do not work on anaerobes

39
Q

Side effects of aminoglycosides

A

Nephrotoxicity and ototoxicity

40
Q

General indications for aminoglycosides

A

UTI, endocarditis, topical skin infections, pneumonia

41
Q

Examples of cephalosporins

A

More brosd spectrum the further you go down

  1. Cefazolin,
  2. Cefotetan
  3. cefotaxime, Ceftriaxone, Cefixime (oral)
  4. Cefepime (with psudomonas cover)
  5. Ceftaroline

Ceftriaxone should not be given with calcium solutions, as it can cause calcium precipitations in the lungs and the kidneys

42
Q

Mechanism of cephalosporins

A

Inhibit cell wall synthesis

43
Q

Side effects of cephalosporins

A

Hypersensitivity and superinfection

44
Q

Examples of carbapenems

A

Doripenem, impenem, meropenem

45
Q

Carbapenems cover

A

Gram positve and gram negative

46
Q

Carbapenems examples

A

Doripenem, Imipenem, Meropenem

47
Q

Penicillins examples

A

Amoxicillin, Piperacillin, Flucloxacillin

Co-amoxiclav / Piptazo

48
Q

Tetracyclines examples

A

tetracycline, doxycycline

49
Q

quinolone examples

A

Ciprofloxacin, Levofloxacin, Moxifloxacin

50
Q

Macrolides examples

A

Clarithromycin, erythromycin

51
Q

Sulfonamides examples

A

Sulfamethoxazole, TMP

52
Q

examples of glycopeptides

A

Vancomycin

53
Q

carbapenems mechanism

A

inhibit cell wall synthesis

54
Q

penicillin mechanism

A

inhibit cell wall synthesis

55
Q

tetracyclines mechanism

A

inhibit protein synthesis

56
Q

quinolones mechanism

A

inhibit DNA Gyrases

57
Q

macrolides mechanism

A

inhibit protein synthesis (50s)

58
Q

sulfonamides mechanism

A

inhibit folic acid

59
Q

glycopeptides mechanism

A

inhibit cell wall synthesis (binds D-Ala - D-Ala terminal –> Transpeptidase inhibition

60
Q

carbapenems side effects

A

GI upset
rash
allergy
seizures in RF

61
Q

penicillin side effects

A

hypersensitivity

neurotoxicity / seizures

62
Q

tetracyclines side effects

A

GI, Renal and liver (reversible) toxicity
Teeth staining
impaired foetal bone growth

63
Q

quinolones side effects

A

cartilage toxicity - archilles heel
peripheral neuropathy
pseudomembranous colitis

64
Q

macrolides side effects

A 
GI upset 
hypersensitivity 
jaundice 
QT prolongation 
CYP450 inhibition
65
Q

sulphonamides side effects

A 
Steven Johnson 
nephrotoxicity 
hyperkalaemia 
neutropenia 
kernicterus
66
Q

glycopeptides side effects

A

nephrotoxicity
ototoxicity
hypotension + flushing
(Red man syndrome)

67
Q

carbapenems coverage

A

gram positive + gram negative

68
Q

penicillins coverage

A

gram positive + gram negative

69
Q

tetracyclines coverage

A

gram positive + gram negative

not staph/ strep generally

70
Q

quinolones coverage

A

gram positive + gram negative

71
Q

macrocodes coverage

A

mostly gram negative

72
Q

sulphonamides coverage

A

gram positive + gram negative

73
Q

glycopeptides coverage

A

gram positive (MRSA)

74
Q

carbapenems indications

A

UTI
Meningitis
Sepsis
Bone + Pelvis + Abdo infections

75
Q

penicillins indications

A

endocarditis
SSTI
URTI / Pneumonia
Neurosyphillis

76
Q

tetracyclines indications

A

Anthrax
C. Tetani
Atypical CAP

77
Q

quinolones indications

A

Resp: Atypical pneumonia
UTI
Gastroenteritis
osteomyelitis

78
Q

macrolides indications

A

resp/sinus/skin infections

chlamydia

79
Q

sulfonamides indications

A

MRSA,

Cystitis due to E.coli

80
Q

glycopeptides indications

A

MRSA
Endocarditis
Pseudomembranous colitis due to C.diff

Core Conditions (13 decks)

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