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FDNS > Antibiotics 1 > Flashcards

Antibiotics 1 Flashcards

1
Q

V (oral), G (IV), Benzathine (IM, longer lasting)

A

Penicillin

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2
Q

Binds penicillin binding protein – inhibits transpeptidase

A

Penicillin

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3
Q

Nafcillin, Dicloxacillin, Antistaph penicillins

A

Penicillinase-resistant penicillins

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4
Q

Same as penicillin, larger R group so resistant to penicillinase

A

Penicillinase-resistant penicillins

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5
Q

Clavulanate (penicillin), Sulbactam, Tazobactam

A

Beta-lactamase inhibitors

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6
Q

Binds irreversibly to beta-lactamase

A

Beta-lactamase inhibitors

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7
Q

Ampicillin, Amoxicillin

A

Amino-penicillins

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8
Q

Water soluble and can pass through porins – same mechanism as penicillin

A

Amino-penicillins

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9
Q

Ticarcillin, piperacillin

A

Anti-pseudomonal penicillin

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10
Q

Same as penicillin, usually only used to treat pseudomonas

A

Anti-pseudomonal penicillin

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11
Q

Monobactum

A

Axtreonam

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12
Q

Monocyclic beta-lactam, same mechanism as penicillin

A

Axtreonam

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13
Q

Excreted by kidney (watch for renal insufficiency)

A

Cephalo-sporins

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14
Q

Same mechanism as penicillin, bacteriocidal beta-lactams

A

Cephalo-sporins

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15
Q

Cephalexin

A

Ceph 1st Gen

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16
Q

Surgical Prophylaxis

A

Ceph 1st Gen

17
Q

Cefoxitin,

A

Ceph 2nd Gen

18
Q

Used immediately prior to surgery

A

Ceph 2nd Gen

19
Q

Ceftriaxone, cefotaxime,
Ceftazidime,
cefdinier

A

Ceph 3rd Gen

20
Q

Cefepime

A

Ceph 4th Gen

21
Q

Ceftaroline

A

Ceph 5th Gen

22
Q

Binds to PBP 2a present in MRSA

A

Ceph 5th Gen

23
Q

Imipenem/

cilastatin meropenem

A

Carbapenems

24
Q

Beta-lactam ring, binds PBP, parenteral admin

A

Carbapenems

25
Q

Bacteriocidal, oral vanco is poorly absorbed

A

Vancomycin

26
Q

Binds to DADA terminus of cell wall precursor unit, inhibits transglycosylase rxn

A

Vancomycin

27
Q

Poor bioavailability, topical ophthalmic and derm preps

A

Bacitracin

28
Q

Prevents dephosphorylation of bactoprenol carrier (needed for elongation of PG cell wall)

A

Bacitracin

29
Q

Bind to LPS, creates holes in outer membrane

bacteriocidal

A

Polymyxin B

30
Q

Binds to cell membrane and aggregates, depolarizes cell

A

Daptomycin

FDNS (12 decks)

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