Antibiotic Summary Flashcards by tom wozny | Brainscape

Q

Fe/Ca/Mag/Al interference with bioavailability

A

flouroquinolones

tetracyclines

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Q

predominantly G+ drugs

A

vanco

dapto

rifampin

fidaxomicin

linezolid

penicillinases

penicillin

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Q

predominantly G- drugs

A

aztrenonam

ceftazidime

cipro

polymyxins

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Q

time dependent

A

TMP/SMZ

B-lactams

linezolid

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Q

exposure dependent

A

tigecycline

tetracyclines

polymyxins

rifampin

macrolides

vanco

clindamycin

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Q

myelosuppression

A

linezolid

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Q

bacteriodes coverage

A

aminopenicillins + inhibitors

extended spec penicillins + inhibitors

carbapenems

cefoxitin

clindamycin

metronidazole

moxifloxacin

tigecycline

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Q

seizures/CNS

A

imipenem

(B-lactams more broadly too)

flouroquinolones

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Q

flouroquinolones that don’t need renal dose adjustment

A

moxifloxacin

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Q

CNS penetration

A

3rd + 4th gen cephalosporins

meropenem

vanco

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Q

high C diff risk

A

clindamycin

flouroquinolones

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Q

very low Vd

A

aminoglycosides

dapto

nitrofurantoin

polymyxins

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Q

B-lactams that don’t need renal dose adjustment

A

ceftriaxone

penicillinases

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Q

pseudo coverage

A

extended spectrum penicillins

cefepime, ceftazidime

dori, mero, imi -penem

aztreonam

gentamicin, tobramycin, amikacin

levo, cipro -floxacin

polymyxins

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Q

G- as well as G+ synergy

A

aminoglycosides

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Q

atypicals coverage

(legionella, myco, chlyamydia)

A

macrolides

tetracyclines

flouroquinolones

Q

MRSA coverage

A

vanco

dapto

linezolid

clindamycin

ceftaroline

tetracyclines

tigecycline

TMP/SMZ

Q

myopathy

A

dapto

Q

predominantly anero

A

metronidazole

Q

G+ and anero

A

clindamycin

Q

nephrotoxic

A

aminoglycosides

polymyxins

vanco

Q

VRE coverage

A

linezolid

dapto

tigecycline (better than tetracyclines)

Q

pulmonary fibrosis

A

nitrofurantoin

Q

rash

A

TMP/SMZ

B-lactams

vanco (Red Man’s)

Q

concentration dependent

A

aminoglycosides

quinolones

dapto

metronidazole