Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CLASP - SEPSIS > Antibiotic Side Effects > Flashcards

Antibiotic Side Effects Flashcards

1
Q

What are the general side effects of all antibiotics?

A

Nausea/Vomiting
Diarrhoea
Rash
Candida Infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the most common allergy to penicillin?

A

Type 1 hypersensitivity reaction => anaphylaxis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Flucloxacillin and co-amoxiclav are known to cause what side effect? How would you monitor this?

A

Cholestatic Jaundice

- check LFTs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What side effects are caused by macrolides?

A

GI disturbance
Hepatitis
Prolonged QT Interval

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What side effects do the quinolones cause?

A

Prolonged QT Interval
Convulsions (lowers seizure threshold)
Tendonitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where in the body do aminoglycosides (e.g. Gentamicin) cause toxicity?

A

Kidney (nephrotoxicity)

Ear (ototoxicity)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How long are aminoglycosides given for to avoid toxicity?

A

3 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What side effect is caused by vancomycin?

A
  • Red man syndrome
  • Histamine mediated reaction
  • Occurs when vancomycin is given too quickly
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How long should a vancomycin infusion take?

A

1hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How are amoxicillin, Gentamicin and Metronidazole all given at the same time?

A

Amoxicillin Bolus
Metronidazole 1 hr infusion
Gentamicin 1 hr infusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What side effects are caused by the tetracyclines?

A

Hepatotoxicity
Teeth staining
Photosensitivity (remind pts to wear high factor sun cream)
Dysphagia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Nitrofurantoin can cause what side effects?

A

Peripheral neuropathy

Interstitial Lung Disease/ Pulmonary Fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Co-trimoxazole and trimethoprim cause what problem in the blood?

A

Dyscrasias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Trimethoprim should be avoided in patients with what underlying disease?

A

Reduced renal function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Chloramphenicol is known to cause what 2 side effects?

A

Aplastic anaemia

Grey Baby

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the consequence of most antibiotics being inhibitors?

A

Cause toxicity of any other drugs the patients is on

17
Q

What effect do antibiotics have on warfarin?

A

Increase INR => decrease effect of warfarin

18
Q

Metronidazole and alochol can cause what complication?

A

projectile vomit

similar to disulfiram reaction

19
Q

What part of the penicillin structure causes the allergic reaction?

A

Beta-lactam ring

house and GARAGE

20
Q

Give an example of an antibiotic which contains a beta-lactam ring however does not usually cause anaphylaxis in penicillin allergic patients?

A

Aztreonam

thiazolidine ring and beta-lactam ring are far away from each other - AKA house and garage

CLASP - SEPSIS (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions