Antibiotic Drugs

Question 1

Which of the following are NOT effective in preventing the emergence or spread of antibiotic resistant pathogens

A. Adherence to hand hygiene
B. Contact isolation during hospitalisation for patients colonised with MRSA
C. Avoiding the use of antibiotics for viral infections
D. Treating infections for a longer duration

Answer 1

D. Treating infections for a longer duration

Question 2

Which of the following is NOT a current example of clinically important antibiotic resistance?

A. Meticillin resistant Staphylococcus aureus
B. Penicillin resistant Streptococcus pyogenes (Group A Strep)
C. Fluoroquinolone resistant P. aeruginosa
D. Vancomycin resistant Enterococci

Answer 2

B. Penicillin resistant Streptococcus pyogenes (Group A Strep)

Question 3

Which of these conditions have become harder to treat because of antibiotic resistance?

A. Gonorrhoea
B. Staphylococcal infections
C. Meningitis
D. All of the above

Answer 3

D. All of the above

Question 4

Which of the following conditions should generally be treated with antibiotic therapy in patients who are not immunosuppressed and not pregnant?

A. Acute bronchitis
B. Asymptomatic urinary tract infection
C. Cellulitis
D. All of the above

Answer 4

C. Cellulitis

Question 5

Which of the following is NOT a way that a bacterium can acquire antibiotic resistance

A. Acquiring resistance gene from its host’s cells
B. On its own through evolution
C. From its parent cell
D. Scavenging resistance genes from the environment

Answer 5

A. Acquiring resistance gene from its host’s cells

Question 6

Which of these antibiotics have useful clinical activity against pseudomonas?

A. Ciprofloxacin
B. Co-amoxiclav
C. Ceftazidime
D. Cefotaxime

Answer 6

A and C

Question 7

Which of these would be suitable to treat Gram positive cocci isolated from a blood culture?

A. Flucloxacillin
B. Vancomycin
C. Ciprofloxacin
D. Trimethoprim

Answer 7

A and B

Question 8

Which of these blood culture results most likely represents a contamination and should NOT automatically be treated with antibiotics?

A. One of two blood culture bottles positive with Group A Streptococci
B. One of two blood culture bottles positive with a gram negative bacterium
C. One of two blood culture bottles positive with coagulase negative Staphylococci
D. One of two blood culture bottles positive with Klebsiella sp.

Answer 8

C. One of two blood culture bottles positive with coagulase negative Staphylococci

Question 9

Which of these conditions needing IV antibiotics could be referred to an outpatient parenteral antibiotic therapy (OPAT) team?

A. Resolving cellulitis needing a further 7 days therapy
B. An ESBL positive urinary tract infection
C. Meningitis – from day 2 of therapy
D. Osteomyelitis needing a further 6 weeks of treatment
E. All of the abov

Answer 9

A, B, and D

Question 10

Which antibiotic(s) can be used in a patient who has had an anaphylactic reaction to penicillin?

A. Cefuroxime
B. Meropenem
C. Gentamicin
D. Ciprofloxacin
E. Clarithromycin
F. All of the above

Answer 10

C, D, and E.