ANTIBIOTIC DRUGS Flashcards
It is also known as prokaryotes which are single-celled organisms that lack a true nucleus and nuclear membrane.
Bacteria
Antibacterial drugs are either obtained from natural sources or are manufactured. True or false?
True.
He discovered the mold that produced Penicillin which was the first antibiotic to be used and marketed?
Alexander Fleming
Enumerate the Five Mechanisms of Antibacterial Action.
- inhibition of bacterial cell-wall
synthesis - alteration of membrane
permeability - inhibition of protein synthesis
- inhibition of the synthesis of bacterial RNA and DNA
- interference with metabolism within the cell.
The pathogen can be inhibited or destroyed when bacteria is __________ to the drug.
Sensitive
The pathogen will continue to grow despite administration when bacteria is __________ to the drug.
Resistant
A type of resistance that occurs without previous exposure to the drug.
Inherent
A type of resistance that is caused by prior exposure to the antibacterial.
Acquired.
What does it called when two drugs are used together, the desired effect may be greatly reduced?
Antagonistic effect
It is the equal to the sum the effects of two antibiotics.
Additive effect
It is called ____________ when signs and symptoms do not improve.
Subtherapeutic
What procedure is recommended for patients with a history of allergic reaction such as itching, hives, rash, swelling or shortness of breath.
Penicillin allergy skin testing
A resistance to one first-line anti-TB drug only.
Monoresistant-TB
What is the most effective antimalarial drug for eradicating the parasite during the exoerythrocytic phase.
Primaquine
Give at least one goal of HAART.
Decrease viral load to undetectable levels
Skipping doses or taking decreased dosages may not cause medication resistance and possible treatment failure. True or False?
False.
It inhibits dihydrofolate reductase, enzyme needed for production of vital substances
Pyrimethamine
Most significant protozoal disease due to high morbidity and mortality.
Malaria.
A tuberculosis that demonstrates resistance to two or more drugs.
Multi-drug resistant TB
When a drug selected is known to be the best drug that can kill the MO, it is called ___________.
Empiric Therapy
