ANTIBIOTIC DRUGS Flashcards

1
Q

It is also known as prokaryotes which are single-celled organisms that lack a true nucleus and nuclear membrane.

A

Bacteria

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2
Q

Antibacterial drugs are either obtained from natural sources or are manufactured. True or false?

A

True.

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3
Q

He discovered the mold that produced Penicillin which was the first antibiotic to be used and marketed?

A

Alexander Fleming

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4
Q

Enumerate the Five Mechanisms of Antibacterial Action.

A
  1. inhibition of bacterial cell-wall
    synthesis
  2. alteration of membrane
    permeability
  3. inhibition of protein synthesis
  4. inhibition of the synthesis of bacterial RNA and DNA
  5. interference with metabolism within the cell.
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5
Q

The pathogen can be inhibited or destroyed when bacteria is __________ to the drug.

A

Sensitive

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6
Q

The pathogen will continue to grow despite administration when bacteria is __________ to the drug.

A

Resistant

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7
Q

A type of resistance that occurs without previous exposure to the drug.

A

Inherent

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8
Q

A type of resistance that is caused by prior exposure to the antibacterial.

A

Acquired.

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9
Q

What does it called when two drugs are used together, the desired effect may be greatly reduced?

A

Antagonistic effect

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10
Q

It is the equal to the sum the effects of two antibiotics.

A

Additive effect

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11
Q

It is called ____________ when signs and symptoms do not improve.

A

Subtherapeutic

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12
Q

What procedure is recommended for patients with a history of allergic reaction such as itching, hives, rash, swelling or shortness of breath.

A

Penicillin allergy skin testing

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13
Q

A resistance to one first-line anti-TB drug only.

A

Monoresistant-TB

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14
Q

What is the most effective antimalarial drug for eradicating the parasite during the exoerythrocytic phase.

A

Primaquine

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15
Q

Give at least one goal of HAART.

A

Decrease viral load to undetectable levels

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16
Q

Skipping doses or taking decreased dosages may not cause medication resistance and possible treatment failure. True or False?

A

False.

17
Q

It inhibits dihydrofolate reductase, enzyme needed for production of vital substances

A

Pyrimethamine

18
Q

Most significant protozoal disease due to high morbidity and mortality.

A

Malaria.

19
Q

A tuberculosis that demonstrates resistance to two or more drugs.

A

Multi-drug resistant TB

20
Q

When a drug selected is known to be the best drug that can kill the MO, it is called ___________.

A

Empiric Therapy