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Prudent use of antibiotics > Antibiotic characteristics > Flashcards

Antibiotic characteristics Flashcards

1
Q

Penicillins (mechanism of action)

A

Inhibition of the cell wall synthesis

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2
Q

Penicillins (mode of action)

A

Time dependent bactericidal

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3
Q

Penicillins (Which group does it belong to?)

A

Beta-lactam antibiotics

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4
Q

Cephalosporins (mechanism of action)

A

Inhibition of the cell wall synthesis

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5
Q

Cephalosporins (mode of action)

A

Time dependent bactericidal

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6
Q

Cephalosporins (Which group does it belong to?)

A

Beta-lactam antibiotics

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7
Q

Narrow spectrum penicillins

A

Benzylpenicillin Na, K
Benzylpenicillin procaine
Benzylpenicillin benzathine
Phenoxymethyl penicillin

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8
Q

Penicillinase stable penicillins

A

Oxacillin
Cloxacillin
Dicloxacillin
Flucloxacillin

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9
Q

Broad spectrum penicillin

A

Amoxicillin

Ampicillin

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10
Q

Penicillins acting against Pseudomonas sp.

A

Ticarcillin

Piperacillin

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11
Q

Cephalosporins 1st generation

A

Cephazoline
Cephapirin
Cefadroxil
cephalexin

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12
Q

Cephalosporins 2nd generation

A

Cefuroxime

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13
Q

Cephalosporins 3rd generation

A 
Ceftiofur
Cefovecin
Ceftriaxone
Cefotaxime
Ceftazidime
Cefoperazone
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14
Q

Cephalosporins 4th generation

A

Cefquinome

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15
Q

Penicillin belongs to which category?

A

Category D (except Amoxicillin clavulanic acid (C) and Piperacillin tazobactam (A))

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16
Q

Cephalosporin generation 1 and 2 belongs to which category?

A

Category C

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17
Q

Cephalosporin generation 3 and 4 belongs to which category?

A

Category B

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18
Q

Carbapenem (mechanism of action)

A

Inhibition of the cell wall synthesis

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19
Q

Carbapenem (mode of action)

A

Time dependent bactericidal

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20
Q

Carbapenem (Which group does it belong to?)

A

Beta-lactam antibiotics

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21
Q

Meropenem belongs to which category?

A

Category A

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22
Q

Monobactams (mechanism of action)

A

Inhibition of the cell wall synthesis

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23
Q

Monobactams (Which group does it belong to?)

A

Beta-lactam antibiotics

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24
Q

Monobactams (mode of action)

A

Time dependent bactericidal

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25
Q

Aztreonam belongs to which category?

A

(Monobactams) Category A

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26
Q

Aminoglycosides (mechanism of action)

A

Inhibition of protein synthesis (30S subunit), mistranslation
Gentamycin does not inhibit the protein synthesis, but non-valid proteins will be created

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27
Q

Aminoglycosides (Mode of action)

A

Concentration dependent bactericidal

Exception! Spectinomycin is bacteriostatic!

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28
Q

Aminoglycosides belongs to which category?

A

Category C

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29
Q

Tetracycline (mechanism of action)

A

Inhibition of protein synthesis (30S subunit)

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30
Q

Tetracycline (Mode of action)

A

Bacteriostatic

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31
Q

Tetracycline belongs to which category?

A

Category D

32
Q

Macrolides (mechanism of action)

A

Inhibition of protein synthesis (50S subunit)

33
Q

Macrolides (Mode of action)

A

Bacteriostatic

34
Q

Macrolides belongs to which category?

A

Category C

35
Q

Lincosamides (mechanism of action)

A

Inhibition of protein synthesis (50S subunit)

36
Q

Lincosamides (Mode of action)

A

Bacteriostatic

37
Q

Lincosamides belongs to which category?

A

Category C

38
Q

Pleuromutilins (mechanism of action)

A

Inhibition of protein synthesis (50S subunit)

39
Q

Pleuromutilins (Mode of action)

A

Bacteriostatic

40
Q

Pleuromutilins belongs to which category?

A

Category C

41
Q

Phenicols (mechanism of action)

A

Inhibition of protein synthesis (50S subunit)

42
Q

Phenicols (Mode of action)

A

Bacteriostatic

43
Q

Phenicols belongs to which category?

A

Category C

44
Q

Polypeptide antibiotics (mechanism of action)

A

They act like a cationic detergent

45
Q

Polypeptide antibiotics (mode of action)

A

Concentration dependent bactericidal

46
Q

Polypeptide antibiotics (Which group does it belong to?)

A

Peptide antibiotics

47
Q

Polymyxin B and Colistin (Polymyxin E) belongs to which category

A

(Polypeptide antibiotics) Category B

48
Q

Glycopeptide antibiotics (mechanism of action)

A

Inhibition of cell wall synthesis

49
Q

Glycopeptide antibiotics (mode of action)

A

Time dependent bactericidal

50
Q

Glycopeptide antibiotics (Which group does it belong to?)

A

Peptide antibiotics

51
Q

Vancomycin belongs to which category

A

(Glycopeptide antibiotics) Category A

52
Q

Rifamycines (mechanism of action)

A

Inhibit bacterial DNA dependent RNA polymerase

53
Q

Rifamycines (mode of action)

A

Time dependent bactericidal

54
Q

Rifampicin belongs to which category

A

Category A

55
Q

Pseudomonic acid (Mupirocin) (mechanism of action)

A

Inhibition of cell wall synthesis

56
Q

Pseudomonic acid (Mupirocin) (mode of action)

A

Bactericidal

57
Q

Pseudomonic acid (Mupirocin) belong to which category?

A

Category A

58
Q

Phosphonic acid derivates (Fosfomycin) (mechanism of action)

A

Inhibition of cell wall synthesis

59
Q

Phosphonic acid derivates (Fosfomycin) (mode of action)

A

Bactericidal

60
Q

Phosphonic acid derivates (Fosfomycin) belong to which category?

A

Category A

61
Q

Fusidic acid (mechanism of action)

A

Inhibition of protein synthesis

62
Q

Fusidic acid (mode of action)

A

Bacteriostatic

63
Q

Sulphonamides (mechanism of action)

A

Inhibition of folic acid synthesis

64
Q

Sulphonamides (mode of action)

A

Separately bacteriostatic and combination time dependent bactericidal

65
Q

Diaminopyrimidines (mechanism of action)

A

Inhibition of folic acid synthesis

66
Q

Diaminopyrimidines (mode of action)

A

Separately bacteriostatic and combination time dependent bactericidal

67
Q

Fluoroquinolones 1st generation

A

Nalidixic acid

68
Q

Fluoroquinolones 2nd generation

A 
Flumequine
Norfloxacin
Orbifloxacin
Ciprofloxacin
Enrofloxacin
Danofloxacin
Difloxacin
Marbofloxacin
69
Q

Fluoroquinolones 3rd generation

A

Levofloxacin

Sparfloxacin

70
Q

Fluoroquinolones 4th generation

A

Pradofloxacin

Moxifloxacin

71
Q

Fluoroquinolones (mechanism of action)

A

Inhibition of DNA synthesis

72
Q

Fluoroquinolones (mode of action)

A

Concentration dependent bactericidal

73
Q

Fluoroquinolones which category does it belong to

A

Category B

74
Q

Nitrofurans (mechanism of action)

A

Destroy the DNA of bacteria

75
Q

Nitrofurans (mode of action)

A

Bactericidal

76
Q

Nitroimidazoles (mechanism of action)

A

Destroy the DNA of bacteria

77
Q

Nitroimidazoles (mode of action)

A

Concentration dependent bactericidal

Prudent use of antibiotics (4 decks)

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