Antibiotic characteristics Flashcards
Penicillins (mechanism of action)
Inhibition of the cell wall synthesis
Penicillins (mode of action)
Time dependent bactericidal
Penicillins (Which group does it belong to?)
Beta-lactam antibiotics
Cephalosporins (mechanism of action)
Inhibition of the cell wall synthesis
Cephalosporins (mode of action)
Time dependent bactericidal
Cephalosporins (Which group does it belong to?)
Beta-lactam antibiotics
Narrow spectrum penicillins
Benzylpenicillin Na, K
Benzylpenicillin procaine
Benzylpenicillin benzathine
Phenoxymethyl penicillin
Penicillinase stable penicillins
Oxacillin
Cloxacillin
Dicloxacillin
Flucloxacillin
Broad spectrum penicillin
Amoxicillin
Ampicillin
Penicillins acting against Pseudomonas sp.
Ticarcillin
Piperacillin
Cephalosporins 1st generation
Cephazoline
Cephapirin
Cefadroxil
cephalexin
Cephalosporins 2nd generation
Cefuroxime
Cephalosporins 3rd generation
Ceftiofur Cefovecin Ceftriaxone Cefotaxime Ceftazidime Cefoperazone
Cephalosporins 4th generation
Cefquinome
Penicillin belongs to which category?
Category D (except Amoxicillin clavulanic acid (C) and Piperacillin tazobactam (A))
Cephalosporin generation 1 and 2 belongs to which category?
Category C
Cephalosporin generation 3 and 4 belongs to which category?
Category B
Carbapenem (mechanism of action)
Inhibition of the cell wall synthesis
Carbapenem (mode of action)
Time dependent bactericidal
Carbapenem (Which group does it belong to?)
Beta-lactam antibiotics
Meropenem belongs to which category?
Category A
Monobactams (mechanism of action)
Inhibition of the cell wall synthesis
Monobactams (Which group does it belong to?)
Beta-lactam antibiotics
Monobactams (mode of action)
Time dependent bactericidal
Aztreonam belongs to which category?
(Monobactams) Category A
Aminoglycosides (mechanism of action)
Inhibition of protein synthesis (30S subunit), mistranslation
Gentamycin does not inhibit the protein synthesis, but non-valid proteins will be created
Aminoglycosides (Mode of action)
Concentration dependent bactericidal
Exception! Spectinomycin is bacteriostatic!
Aminoglycosides belongs to which category?
Category C
Tetracycline (mechanism of action)
Inhibition of protein synthesis (30S subunit)
Tetracycline (Mode of action)
Bacteriostatic
Tetracycline belongs to which category?
Category D
Macrolides (mechanism of action)
Inhibition of protein synthesis (50S subunit)
Macrolides (Mode of action)
Bacteriostatic
Macrolides belongs to which category?
Category C
Lincosamides (mechanism of action)
Inhibition of protein synthesis (50S subunit)
Lincosamides (Mode of action)
Bacteriostatic
Lincosamides belongs to which category?
Category C
Pleuromutilins (mechanism of action)
Inhibition of protein synthesis (50S subunit)
Pleuromutilins (Mode of action)
Bacteriostatic
Pleuromutilins belongs to which category?
Category C
Phenicols (mechanism of action)
Inhibition of protein synthesis (50S subunit)
Phenicols (Mode of action)
Bacteriostatic
Phenicols belongs to which category?
Category C
Polypeptide antibiotics (mechanism of action)
They act like a cationic detergent
Polypeptide antibiotics (mode of action)
Concentration dependent bactericidal
Polypeptide antibiotics (Which group does it belong to?)
Peptide antibiotics
Polymyxin B and Colistin (Polymyxin E) belongs to which category
(Polypeptide antibiotics) Category B
Glycopeptide antibiotics (mechanism of action)
Inhibition of cell wall synthesis
Glycopeptide antibiotics (mode of action)
Time dependent bactericidal
Glycopeptide antibiotics (Which group does it belong to?)
Peptide antibiotics
Vancomycin belongs to which category
(Glycopeptide antibiotics) Category A
Rifamycines (mechanism of action)
Inhibit bacterial DNA dependent RNA polymerase
Rifamycines (mode of action)
Time dependent bactericidal
Rifampicin belongs to which category
Category A
Pseudomonic acid (Mupirocin) (mechanism of action)
Inhibition of cell wall synthesis
Pseudomonic acid (Mupirocin) (mode of action)
Bactericidal
Pseudomonic acid (Mupirocin) belong to which category?
Category A
Phosphonic acid derivates (Fosfomycin) (mechanism of action)
Inhibition of cell wall synthesis
Phosphonic acid derivates (Fosfomycin) (mode of action)
Bactericidal
Phosphonic acid derivates (Fosfomycin) belong to which category?
Category A
Fusidic acid (mechanism of action)
Inhibition of protein synthesis
Fusidic acid (mode of action)
Bacteriostatic
Sulphonamides (mechanism of action)
Inhibition of folic acid synthesis
Sulphonamides (mode of action)
Separately bacteriostatic and combination time dependent bactericidal
Diaminopyrimidines (mechanism of action)
Inhibition of folic acid synthesis
Diaminopyrimidines (mode of action)
Separately bacteriostatic and combination time dependent bactericidal
Fluoroquinolones 1st generation
Nalidixic acid
Fluoroquinolones 2nd generation
Flumequine Norfloxacin Orbifloxacin Ciprofloxacin Enrofloxacin Danofloxacin Difloxacin Marbofloxacin
Fluoroquinolones 3rd generation
Levofloxacin
Sparfloxacin
Fluoroquinolones 4th generation
Pradofloxacin
Moxifloxacin
Fluoroquinolones (mechanism of action)
Inhibition of DNA synthesis
Fluoroquinolones (mode of action)
Concentration dependent bactericidal
Fluoroquinolones which category does it belong to
Category B
Nitrofurans (mechanism of action)
Destroy the DNA of bacteria
Nitrofurans (mode of action)
Bactericidal
Nitroimidazoles (mechanism of action)
Destroy the DNA of bacteria
Nitroimidazoles (mode of action)
Concentration dependent bactericidal