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MICROM 301 > Antibacterial Meds > Flashcards

Antibacterial Meds Flashcards

1
Q

Cell Wall Synthesis Antibiotic Class

A

ß-lactam
Penicillins
Cephalosporins
Carabapenems
Monobactams
Glycopeptide Antibiotics
Bacitracin

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2
Q

Class: ß-lactam Antibiotics

A

Penicillins, Cephalosporins, Carabapenems, monobactams

high therapeutic index

Interferes with peptidoglycan synthesis by PBPs

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3
Q

Natural Penicillins - function

A

Original Penicillins prod by Penicillium Chrysogenum

Narrow-Spectruum

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4
Q

Natural Penicillins - Effectiveness

A

narrow spectrum

gram positive and a few gram negative bac

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5
Q

Natural Penicillin - Med + Application

A

Penicillin V - Orally
Penicillin G - IV or IM

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6
Q

Penicillinase-Resisitant Penicillins - Effectiveness

A

Some staphlococcus aureus prod Penicillinase that destroy natural Penicillin molecules and make them ineffective. Resistant Penicillins are resistant to these strains

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7
Q

Penicillinase-Resisitant Penicillins - Med

A

Methicillin and Dicloxacillin

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8
Q

PBP2a + Strain Name

A

Altered PBP that destroys Penicillinase-Resisitant Penicillin

MRSA

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9
Q

MRSA

A

Methicillin-resistant S. Aureus

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10
Q

Broad-spectrum penicillins - effectiveness

A

effective against many penicillin sensitive gram positive and many gram negative bacteria

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11
Q

Broad-spectrum penicillins - flaw

A

inactivated by many ß-lactamases

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12
Q

Broad-spectrum penicillins - med

A

ampicillin and amoxicillin

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13
Q

Extended-spectrum penicillins - effectiveness

A

Greater activity against most enterobacteriaceae and Pseudomonoas aeruginosa

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14
Q

Extended-spectrum penicillins - flaw

A

less activity against gram positive bacteria

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15
Q

Extended-spectrum penicillins - med

A

Ticarcillin and piperacillin

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16
Q

Penicillins + ß-lactamase inhibitor - function

A

Combination of ß-lactamase inhibitor and some type of penicillin

17
Q

Augmentin - combo mix

A

amoxicillin (penicillin) and clavulanic acid (ß-lactamase inhibitor)

MICROM 301 (7 decks)

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