Antibacterial Agents

Question 1

What type of reactions are most commonly seen with penicillin?

Answer 1

Allergic reactions

Question 2

Name the penicillin’s

Answer 2

Penicillin G, Penicillin V, Cloxacillin, Amoxicillin, Ampicillin, Clavulanic acid

Question 3

Ampicillin/ amoxicillin fall under what range on the spectrum?

Answer 3

Broad +/-

Question 4

Amoxicillin/ clavulanic acid fall under what range on the spectrum?

Answer 4

Potentiated

Question 5

What are Cephalosporins?

Answer 5

Close relation to penicillin, 1-4 generations, narrow to broad spectrum depending on the generation

Question 6

What are the potential toxicities of Tetracylcines?

Answer 6

Discoloration of teeth, esophageal stricture in cats

Question 7

What are the potential toxicities of Sulfonamides?

Answer 7

Crystalluria

Question 8

What patients should you not prescribe Aminoglycosides to?

Answer 8

Patients with renal disease - nephrotoxicity

Question 9

This antibacterial is contraindicated in use for rabbits, hamsters, chinchillas, guinea pigs, horses and ruminants

Answer 9

Lincosamides

Question 10

This antibacterial is fatal if injected into humans

Answer 10

Macrolides

Question 11

What are the potential toxicities of fluoroquinolones (Enrofloxacin)

Answer 11

Interfere with cartilage in puppies, retinal damage in cats

Question 12

Polypeptide antibiotics can only be given ______________

Answer 12

Topically

Question 13

What antibacterial’s cannot be used in food animals?

Answer 13

Chloramphenicol, Nitrofurans, Nitroimidazole

Question 14

Nitrofurans are considered to be a human _______________

Answer 14

carcinogen

Question 15

What is a potential toxicity of Nitroimidazole?

Answer 15

Neurologic toxicity

Question 16

What is a potential toxicity of Chloramphenicol?

Answer 16

Aplastic anemia - bone marrow toxicity

Question 17

What are the bactericidal’s?

Answer 17

Penicillin, Cephalosporin, Aminoglycosides, Fluoroquinolones, Polypeptides, Nitrofurans, Nitroimidazole

Question 18

What are the bacteriostatic’s?

Answer 18

Tetracyclines, Sulfonamides, Lincosamides, Macrolides, Chloramphenicol

Question 19

Tetracyclines fall where in the spectrum?

Answer 19

Broad

Question 20

Sulfonamides fall where on the spectrum?

Answer 20

Broad

Question 21

Aminoglycosides fall where on the spectrum?

Answer 21

Narrow gram -

Question 22

Lincosamides fall where on the spectrum?

Answer 22

Narrow gram +

Question 23

Macrolides fall where on the spectrum?

Answer 23

Variable

Question 24

Fluoroquinolones fall where on the spectrum?

Answer 24

Broad

Question 25

Polypeptides fall where on the spectrum?

Answer 25

Narrow gram - / narrow gram +

Question 26

Chloramphenicol’s fall where on the spectrum?

Answer 26

Broad

Question 27

Nitrofurans fall where on the spectrum?

Answer 27

Broad

Question 28

Nitroimidazole’s fall where on the spectrum?

Answer 28

Narrow

Question 29

What are the possible toxicities of Doxycycline (tetracycline)?

Answer 29

Esophageal stricture in cats

Question 30

What are the potential toxicities of Sulfonamides?

Answer 30

KSC - Keratoconjunctivitis in dogs, crystalluria

Question 31

Polymyxin B has what potential toxicities?

Answer 31

Nephrotoxic, neurotoxic

Question 32

Bacitracin (Polypeptide) has what potential toxicities?

Answer 32

Nephrotoxic

Question 33

What is a potential toxicity of Aminoglycosides?

Answer 33

Ototoxicity, nephrotoxicity