Antiarrythm

Question 1

Anti-arry drug classes:

Answer 1

SOME BLOCK POTASSIUM CHANNELS

Class I: Sodium
Class II: Beta Blockers
Class III: Potassium
Class IV: Calcium

Question 2

Class I divisions

Answer 2

Sodium blockers.

Double quarter pounder,
lettuce tomato mayo
Fries please

IA Disopyramide, Quinidine, procainamide,
IB lidocaine, mexiletine, tocainide,
IC Flecainide, propafenone.

Question 3

What is the potency of class I antiarrh?

Answer 3

IC>IA>IB

Question 4

What are class II anti-arry?

Answer 4

Beta blockers

Question 5

What are drugs in class III anti-arry?

Answer 5

Class III IS BAD

Ibutilide
Sotalol
Bretylium
Amiodarone
Dofetilide/Dronedarone

Question 6

What are they drugs of class IV?

Answer 6

Verapamil
Diltazem

Question 7

What are the drugs given for Afib?

Answer 7

1st cardiovert- Ibutilide
Then use AVN blockers: CCB, b-blockers, digitalis, or amiodarone
+
Thromoembolic events- antiplatelets and anticoagulants

Question 8

How do you maintain a NSR with chronic therapy for AFib?

Answer 8

Dofetilide
- but check for ventricular tach- QT

Question 9

Class I agents are being pursued becuase?

Answer 9

Increased mortality

Question 10

What is the best medication to give patients post MI?

Answer 10

B blockers

Question 11

When do you use Adenosine?

Answer 11

Adenosine slows conduction through the AVN.

Good for ventricular porblems.

Question 12

When do you use digoxin?

Answer 12

It increases vagal tone, parasympathetics. Good for Afib in pt with HF.

Question 13

When do you use atropine?

Answer 13

To treat bradycardia

Question 14

What is the most effective AAD for atrial and ventricular arrhythmias?

Answer 14

Amio- but its TOXIC.

Question 15

Many AADs have a _ QT interval which predisposes the a _ _ _ called _ _ _

Answer 15

Increased QT
Polymorphic ventricular tachycardia
Torsades de pointes