Antianginal Drugs Flashcards
1
Q
Three classes
A
- Nitrates/nitrites
- Beta blockers
- Calcium channel blockers
2
Q
Nitrates/nitrites
A
3
Q
Stable angina
A
- goes away with rest and treatment
4
Q
Unstable angina
A
- unexpected
- even when resting
5
Q
Vasospastic angina
A
- caused by a spasm of coronary artery
6
Q
Rapid-acting forms of nitrates/nitrites
A
- treat anginal attacks
- sublimgual
- IV infusion
7
Q
Long-acting forms of nitrates/nitrites
A
- prevent anginal episodes
8
Q
Nitrates/nitrites MOA
A
- vasodilation of coronary arteries
- relaxation of smooth muscle
9
Q
Oral nitroglycerin
A
- first-pass effect makes this a less effective choice
10
Q
SL nitroglycerin
A
for acute onset or prevention
11
Q
IV nitroglycerin
A
- for BP control
- tx of ischemic pain
- HF
- pulmonary edema
12
Q
topical nitroglycerin
A
- continuous slow delivery
- worn 12-14h/day
13
Q
Nitroglycerin contraindications
A
- anemia
- CA glaucoma
- hypotn
- head injury
- ED drugs
14
Q
Nitroglycerin AE
A
- HA
- tachy
- postural hypotn
- dermatitis (topical)
- tolerance development
15
Q
Nitroglycerin interactions
A
- ETOH
- beta-blockers
- calcium channel blockers
- ED drugs (severe hypotn)
