anti TB drugs

Question 1

isoniazid

Answer 1

specific for myobacteria inhibits growth of bacterium
treats both active and latent TB
peripheral nephrotoxity, hepatotoxity, hyperglycemia
active TB observation is done to ensure medication compliance
labs - liver, glucose

Question 2

rifampin

Answer 2

bactericidal inhibits protein synthesis
treatments of TB given in combination with another anti TB medication to prevent antibiotic resistance
discoloration of body fluids, hepatoxicity, GI discomfort, pseudomembranous colitis
will turn urine sweat, salvia and tears orange no contact lenses
take medication w a glass of water 1-2 hrs before or after meals
use non hormonal form of birth control
improvement of TB s&s
three negative sputum cultures taking 3-6 months