Anti-Psychotics

Question 1

Which anti-psychotic is effective in treatment-resistant Schizophrenia?

Answer 1

Clozapine.

Question 2

Which drug(s) have these side effects: 
Moderate sedation, and severe anti-muscarinic effects but fewer EPS.

Answer 2

Periciazine

Pipotiazine

Question 3

What are the side effects of Chlorpromazine?

Answer 3

Moderate anti-muscarinic and EPS.
Also endocrine – hypotensive SEs.
Pronounced sedative.

Question 4

Which drug is sedating, but is worn off with repeated administration?

Answer 4

Chlorpromazine
Levomepromazine
Promazine

Question 5

Which 1st generation antipsychotic has a high D2 receptor affinity?

Answer 5

Haloperidol.

Question 6

Which 2nd generation antipsychotic has a long half-life?

Answer 6

Aripiprazole.

Question 7

Which drug comes with the risk of agranulocytosis? What should you monitor?

Answer 7

Drug = Clozapine.
Monitor = WBC count.

Question 8

Name 2 Group 3 Phenothiazines.

Answer 8

Fluphenazine

Prochlorperazine

Question 9

Which drug has low clinical potency?

Answer 9

Chlorpromazine.

Question 10

Which drug(s) have this side effects profile:
Little or no EPS, or ANS and cardiac side effects at low doses.

Answer 10

Risperidone.

Question 11

Which 2nd generation antipsychotic is more potent than clozapine?

Answer 11

Risperidone.