Anti-Psychotics

Question 1

Indications for use of anti-psychotics

Answer 1

Schizophrenia
Schizoaffective Disorders
Bipolar
Psychotic depression

Question 2

What are the 2 main groups of anti-psychotics

Answer 2

Typical

Atypical

Question 3

Are typical or atypical anti-psychotics recommended 1st line for schizophrenia

Answer 3

Atypicals

Question 4

What are the 2 broad types of typical anti-psychotics

Answer 4

High potency typical

Low potency typical

Question 5

What is the mode of action typically

Answer 5

D2 dopamin receptor antagonist

Question 6

Action of high potency typicals

Answer 6

High potency typical bind to D2 receptor with high affinity

Question 7

Action of low potency typicals

Answer 7

Have less affinity for D2 receptors

But tend to interact with non-dopaminergic receptors

Question 8

Drug examples of high potency typicals

Answer 8

Fluphenazine
Haloperidol
Pimozide

Question 9

Drug examples of low potency typicals

Answer 9

Chlorpromazine

Thioridazine

Question 10

Action of atypical

Answer 10

Serotonin dopamin 2 antagonists

Question 11

Drug examples of atypical

Answer 11

Risperidone 
Olanzapine 
Quetiapine 
Aripiprazole 
Clozapine

Question 12

What is the most common cause of relapse in psychosis

Answer 12

Lack of insight which leads to lack of compliance

Question 13

Which anti-psychotic is reserved for treatment resistant patients

Answer 13

Clozapine

Question 14

Are typicals or atypical more likely to cause extra-pyramidal side effects

Answer 14

Typicals