Anti-protozoaire middelen Flashcards

1
Q

Giardia

A
  • Metronidazole (Fe, Ca)

- Albendazole, Fenbendazole

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2
Q

Toxoplasma gondii

A
  • Sulfonamiden-trim
  • Clindamycine
  • Spiramycine
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3
Q

Cryptosporidium

A
  • Paromomycine
  • Azithromycine
  • Halofuginone
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4
Q

Babesiose

A
  • Imidocarb (Ca, EQ, Bo, NIET Fe)

- Doxycycline (Ca, Fe, EQ, Bo)

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5
Q

Neospora canis

A
  • Sulfadiazine-trimethoprim
  • Clindamycine
  • Ponazuril
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6
Q

Nitro-imidazoles

A
  • Metronidazole
  • Dimetronidazole
  • Ronidazole
  • Carnidazole
    ! Carcinogeen: niet bij voedselproducerende dieren
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7
Q

Gebruik nitro-imidazoles

A

Trichomonas gallinae
Histomonas meleagridis
Giardia, Entamoeba histolytica, etc.

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8
Q

Anti-coccidiose middelen

A
  • Sulfonamiden
  • Amprolium
  • Triazine derivaten
  • Decoquinaat
  • Nicarbazine
  • Robenidine
  • Halofuginone
  • Ionofore coccidiostatica
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9
Q

Sulfonamiden

A
  • Sulfaquinoxaline
  • Sulfamethazine
  • Sulfadimethoxine
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10
Q

Werkingsmechanisme sulfonamiden

A

Inhibitie foliumzuursynthese

Combinatie met pyrimidines: trimethoprim/ormethoprim

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11
Q

Gebruik sulfonamiden

A

Preventief en curatief

Intestinale coccidia

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12
Q

Amprolium

A

Vit. B1 antagonist
Preventief + curatief gebruik
+ sulfonamiden/trimethoprim

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13
Q

Triazine derivaten

A

W: inhibitie dihydroorotaat synthetase: geen vorming van pyrimidines

  • Diclazuril
  • Toltrazuril
  • Ponazuril
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14
Q

Diclazuril

A

Preventief bij mestkip, kalkoen, big, lam/kalf

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15
Q

Toltrazuril

A

Preventief + curatief bij pluimvee, big, lam/kalf en hond

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16
Q

Ponazuril

A

Geregistreerd voor EPM paard

Off-label voor coccidiose bji KHD en Toxoplasma

17
Q

Decoquinaat

A

W: inhibitie gyrase/elektronentransport

Preventief

18
Q

Nicarbazine

A

W: inhibitie elektronentransport
Preventief
NIET bij leghennen: daling eileg en eigewicht, verdunning eischaal
Mestkip enkel bij opstart (groei)

19
Q

Robenidine

A

W: guanidine analoog
Preventief
NIET bij leghennen

20
Q

Ionofore coccidiostatica

A
  • Monovalente ionoforen: monensin, narasin, salinomycine
  • Glycoside monovalente ionoforen: maduramycine, semduramycine
  • Divalente ionoforen: Lasalocid
    !!! Cardiotoxisch voor Eq, konijn en kalkoen !!!
    Interactie met pleuromutilines