Anti-Platelet Drugs Flashcards

1
Q

Aspirin

A

Irreversible COX inhibitor

Prevents TxA2 Production (normally induces GPIIa/IIIb expression)

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2
Q

Clopidogrel

A

Once activated by P-450, irreversible antagonizes ADP receptors.
ADP usually upregulates GPIIa/IIIb

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3
Q

Abciximab

A

Monoclonal antibody against IIb/IIIa

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