Anti-platelet Flashcards

1
Q

What are examples of anti-platelet medications?

A

NSAID, ADP receptors P2Y12 blocker, GPIIb/Illa Receptor blockers, PDE (3) inhibitor

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2
Q

What are examples of NSAID medications?

A

Aspirin

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3
Q

What is the MOA of NSAIDS?

A

COX-1 inhibitors; prevents formation of thromboxane A2

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4
Q

What are examples of ADP receptors P2Y12 blocker?

A

Clopidogrel, prasugrel, ticagrelor

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5
Q

What is the mOA of ADP receptors P2Y12 blocker?

A

Blocks ADP activation of process the signals fibrinogen linking of platelets

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6
Q

What are examples of GPIIb/Illa Receptors blockers?

A

Abciximab, tirofiban, eptifibatide

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7
Q

What is the MOA with GPIIb/Illa Receptor blockers?

A

Blocks GPIIb/IIIa receptor activity of fibrin linking platelets together

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8
Q

What are examples of PDE (3) inhibitor?

A

Dipyridamole, cilostazol

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9
Q

What is the MOA of PDE (3) inhibitor?

A

Inhibition of platelet activation. Also has vasodilation properties

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10
Q

What do anti-platelet medications do?

A

prevent platelet aggregation by acting on receptors or biochemical processes in the platelet cell or preventing the formation of compounds necessary for these processes to occur

** prevents platelets from clumping to prevent the formation and growth of clots

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