Anti malarials and antivirals Flashcards
What is the only malaria treatment?
Primaquine
Name the drug classes used to prevent malaria
Rapid and slow acting schizonticides
Name 3 rapid acting schizonticides
Mefloquine, chloroquine, quinine
Name 2 slow acting schizonticides
Pyrimethamine, proguanil
What is mefloquine?
A rapid acting schizonticide
What is chloroquine?
A rapid acting schizonticide
What is quinine?
A rapid acting schizonticide
What is proguanil?
A slow acting schizonticide
Name some combination preparation antimalarials
Maloprim (pyriethamine+ dapsone)
Fansidar (pyrimethamine+ sulphadoxine)
Malarone (proguanil+ atovaquone)
What is malarone?
Proguanil + atovaquone
What is fansidar?
Pyrimethamine+ suphadoxine
What is maloprim?
Pyrimethamine+ dapsone
Name 5 categories of antiviral drugs
Protease inhibitors Fusion inhibitors Uncoating inhibitors Nucleic acid inhibitors Release blockers
Name 3 nucleic acid inhibitors
Acyclovir (herpes, DNA polymerase inhib)
Nevirapine (non nucleoside HIV)
Zidovudine (nucleoside HIV) SE bone marrow suppression and anaemia
Name a protease inhibitor
Indinavir (HIV)