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GI Anatomy and Pharmacology > Anti fungals > Flashcards

Anti fungals Flashcards

1
Q

What are the 3 main classes of antifungals?

A

Polyenes, triazoles and imidazoles

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2
Q

Name 2 polyenes

A

Amphoteracin

Nystatin

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3
Q

Name 3 imidazoles

A

Ketoconazole, clotrimazole, miconazole

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4
Q

Name 3 triazoles

A

Fluconazole, itraconazole, voriconazole

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5
Q

If an anti fungal ends in -conazole what class is it?

A

A triazole or imidazole

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6
Q

Name the antifungal that is a squalene epoxidase inhibitor

A

Terbinafine

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7
Q

Which antifungal is a nucleic acid synthesis inhibitor?

A

Flucytosine

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8
Q

What is griseofulvin?

A

An antifungal that inhibits the mitotic spindle

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9
Q

What is clotrimazole?

A

An imidazole antifungal

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10
Q

What is nystatin?

A

A polyene antifungal

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11
Q

What is amphoteracin?

A

A polyene antifungal

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12
Q

What is itraconazole?

A

A triazole antifungal

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13
Q

What is terbinafine?

A

An antifungal that inhibits squalene epoxidase

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14
Q

How do triazoles and imidazoles work?

A

Cell wall synthesis inhibitor, inhibits lanosterol demethylase

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15
Q

How would you treat dermatophytes?

A

Itraconazole, clotrimazole

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16
Q

How would you treat vaginal candidiasis?

A

Clotrimazole

17
Q

How would you treat systemic mycoses?

A

Ketoconazole

18
Q

SE of ketoconazole

A

Can bock adrenal gland hormone production and steroid formation

GI Anatomy and Pharmacology (9 decks)

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