Anti-lipids Medication Flashcards
Dyslipidaemia
1
Q
What is the mechanism of action of Statins?
A
Statins competitively inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, an enzyme involved in cholesterol synthesis, especially in the liver.
2
Q
What is a common adverse effect of statin use, especially if given in high doses?
A
Myositis, Myopathy and Rhabdomyolysis
3
Q
Which patients are at high risk of experiencing adverse effects from statin use?
A
Patients at high risk includes those with a personal or family history of muscular disorders, previous history of muscular toxicity, a high alcohol intake, renal impairment or hypothyroidism.
