Anti-inflammatory and immunosuppressant agents

Question 1

prostaglandin E

Answer 1

increased pain and edema in response to bradykinin , pyresis

decreased gastric secretion, gastric mucosal protection

Question 2

prostaglandin F

Answer 2

decreased gastric secretion, gastric mucosal protection

Question 3

prostacyclin

Answer 3

inhibition of platelet aggregation, vasodilation

Question 4

thromboxane A2

Answer 4

platelet aggregation, vasoconstriction

Question 5

HETE

Answer 5

chemotaxis of leukocytes and alveolar macrophages

Question 6

leukotrienes

Answer 6

role in anaphylaxis, increase vascular permeability, bronchconstriction, chemotaxis of leukocytes

Question 7

diphenhydramine

Answer 7

first gen H1 receptor antagonist

Question 8

loratadine

Answer 8

2nd gen H1 receptor antagonist

Question 9

non-opioid analgesics

Answer 9

acetaminophen, aspirin, ibuprofen

Question 10

NSAIDs

Answer 10

aspirin, ibuprofen

Question 11

celecoxib

Answer 11

COX 2 inhibitor

Question 12

methotrexate

Answer 12

DMARDS

Question 13

infliximab

Answer 13

TNFa inhibitor

Question 14

hydrocortisone

Answer 14

(cortisol) endogenous glucocorticoids

Question 15

synthetic glucocorticoids

Answer 15

cortisone, prednisone, dexamethasone