anti-infectives 2 Flashcards

1
Q

are medications designed to combat viral infections by interfering with the virus’s ability
to replicate and spread within the body

A

antiviral

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2
Q

directly bind to specific proteins on the virus’s surface, known as viral spike proteins, which are responsible for attaching to host cells

A

blocking viral receptors

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3
Q

This prevents the virus from recognizing and binding to the host cell’s receptors, effectively blocking its entry.

A

blocking viral receptors

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4
Q

target the host cell receptors that viruses use to
attach. These drugs can either block the receptor directly or alter its structure, making it unrecognizable to the virus.

A

interfering with hist cell receptors

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5
Q

This drug targets the gp41 protein on the HIV virus, preventing it from fusing with the host cell membrane and entering the cell.

A

Enfuvirtide

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6
Q

This drug blocks the CCR5 receptor on host cells, which HIV uses as a co-receptor for entry.

A

Maraviroc (selzentry)

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7
Q

targets the gp120 subunit within the HIV-1 gp160 envelope glycoprotein, preventing the virus from attaching to the host cell

A

Fostemsavir (rukobia)

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8
Q

Its antiviral mechanism involves antagonism of the influenza A M2 proton channel. This blockage prevents endosomal escape, which is the release of viral genetic
material into the host cytoplasm.

A

Amantadine

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9
Q

an example of nucleotide analog that specifically target reverse transcriptase, an
enzyme used by retroviruses (like HIV) to convert their RNA genome into DNA.

A

Acyclovir

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10
Q

it prevents HIV from integrating its genetic material into the host cell’s DNA, thus stopping the virus from replicating and spreading

A

Dolutegravir

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11
Q

widely used antiviral medication that effectively treats infections caused by herpes viruses, including herpes simplex virus (HSV) and varicella-zoster virus (VZV).

A

Acyclovir

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12
Q

Interferes with this process by being incorporated into the viral DNA chain, effectively stopping further DNA synthesis and viral replication

A

Acyclovir

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13
Q

Antiviral drugs

A
  1. Enfurirtide
  2. Maraviroc (selzentry)
  3. Fostemsavir (Rukobia)
  4. Amantadine
  5. Acyclovir
  6. Dolutegravir
  7. Acyclovir
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14
Q

also known as antimycotic agents, are a class of drugs used to treat and prevent fungal infections

A

Anti-fungal medications

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15
Q

work by targeting specific processes or structures essential for fungal survival but not present in human cells

A

Anti-fungal

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16
Q

Types of Antiparasitic Drugs

A
  1. Ketoconazole (nizoral)
  2. Amphotericin B
  3. Fluconazole
  4. Griseofulvin
17
Q

Interfere with parasite metabolism and reproduction

A

Anti-parasitic

18
Q

Antiparasitic Drugs:

A
  1. Antiprotozoal agents
  2. Antihelminthic agents
  3. Amebicides
  4. Ectoparasiticides
19
Q

Common anti-parasitic drugs

A
  1. Antiprotozoal
  2. Antihelminthic
  3. Amebicides
  4. Ectoparasiticides
20
Q

Antihelminthic

A

Albendazole
Mebendazole

21
Q

is effective against a wide range of intestinal parasites, including roundworms, tapeworms, and flukes.

A

Albendazole

22
Q

effective against Ascariasis, pinworm Enterobius vermicularis,
hookworms such as Ancylostoma caninum and Necator americanus, oundworm
Trichinella spiralis.

A

Mebendazole

23
Q

Amebicides

A

a. Chloroquine
b. Metronidazole

24
Q

Ectoparasiticides

A

Permethrin (kwell)