anti-infectives 2 Flashcards
are medications designed to combat viral infections by interfering with the virus’s ability
to replicate and spread within the body
antiviral
directly bind to specific proteins on the virus’s surface, known as viral spike proteins, which are responsible for attaching to host cells
blocking viral receptors
This prevents the virus from recognizing and binding to the host cell’s receptors, effectively blocking its entry.
blocking viral receptors
target the host cell receptors that viruses use to
attach. These drugs can either block the receptor directly or alter its structure, making it unrecognizable to the virus.
interfering with hist cell receptors
This drug targets the gp41 protein on the HIV virus, preventing it from fusing with the host cell membrane and entering the cell.
Enfuvirtide
This drug blocks the CCR5 receptor on host cells, which HIV uses as a co-receptor for entry.
Maraviroc (selzentry)
targets the gp120 subunit within the HIV-1 gp160 envelope glycoprotein, preventing the virus from attaching to the host cell
Fostemsavir (rukobia)
Its antiviral mechanism involves antagonism of the influenza A M2 proton channel. This blockage prevents endosomal escape, which is the release of viral genetic
material into the host cytoplasm.
Amantadine
an example of nucleotide analog that specifically target reverse transcriptase, an
enzyme used by retroviruses (like HIV) to convert their RNA genome into DNA.
Acyclovir
it prevents HIV from integrating its genetic material into the host cell’s DNA, thus stopping the virus from replicating and spreading
Dolutegravir
widely used antiviral medication that effectively treats infections caused by herpes viruses, including herpes simplex virus (HSV) and varicella-zoster virus (VZV).
Acyclovir
Interferes with this process by being incorporated into the viral DNA chain, effectively stopping further DNA synthesis and viral replication
Acyclovir
Antiviral drugs
- Enfurirtide
- Maraviroc (selzentry)
- Fostemsavir (Rukobia)
- Amantadine
- Acyclovir
- Dolutegravir
- Acyclovir
also known as antimycotic agents, are a class of drugs used to treat and prevent fungal infections
Anti-fungal medications
work by targeting specific processes or structures essential for fungal survival but not present in human cells
Anti-fungal