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Pharm test 4 > Anti-hypertensive drugs > Flashcards

Anti-hypertensive drugs Flashcards

1
Q

First line drugs for hypertensino

A

diuretics, CCBs, ACEi, ARBs

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2
Q

NIfedipine class and MOA

A

CCB: dihydropyridine…dilates vascular smooth muscle

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3
Q

Nifedipine AE

A

acute tachycardia, peripheral edema

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4
Q

Clonidine class and MOA

A

sympatholytic drug, centrally acting… reducing sympathetic outflow from CNS

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5
Q

Clonidine AE

A

sedation, dry mough, dermatitis

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6
Q

Methyldopa class and MOA

A

same as clonidine central acting sympatholytic drug

note: USED IN PREGNANCY

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7
Q

Reserpine class and MOA

A

indirect acting adrenergic blocking agent… stoping vesicular storage
note: normally combined with diuretics

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8
Q

Reserpine AE

A

depression, nasal congestion

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9
Q

Phenoxybenamein class and indication

A

non selective a blocker…used in pheochromocytoma

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10
Q

Pehenoxybenazmine AE

A

tachycardia

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11
Q

Prazosin class

A

selective a1 antagonist

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12
Q

prazosin substitutes

A

terazosin, doxasosin

have longer half lives

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13
Q

prazosin AE

A

hypotension

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14
Q

nonselective BB

A

propranolol, nadolol, pindolol

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15
Q

selective BB

A

Esmolol, metoprolol, atenolol

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16
Q

BB with alpha activitiy

A

Labetolol, and carvedilol

17
Q

BB contraindications

A

Cardio shock, bradycardia, asthma, hf, also masks hypoglycemia in diabetics

18
Q

minoxidil

A

vasodilator

19
Q

other vasodilators

A

hydralazine, nitroprusside

both for emergencies

20
Q

ACEi drugs

A 
captopril (short 1/2)
elanapril
Lisinopril (1 day dosing)
21
Q

Acei AE

A

hyperkalemia, dry cough, angioedema

contra: pregnancy bilateral renal stenosis

22
Q

Losartan class ad MOR

A

ARB

23
Q

Losartan AE

A

hyperkalemia

contra in PREGNANCY

Pharm test 4 (11 decks)

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