Anti‐Diarrhoeals

Question 1

Anti‐Diarrhoeals types?

Answer 1

1. Opioid Agonist
2. Kaolin & Pectin
3. Somatostatin like peptides
4. Resins
5. Lysophilizate

Question 2

Opioid Agonist drugs?

Answer 2

Loperamide, also check for atropine

Question 3

Opioid Agonist mechanism of action?

Answer 3

Increase colonic transit time

Question 4

Opioid Agonist side effects and contraindications?

Answer 4

Constipation

Question 5

Kaolin & Pectin mechanism of action?

Answer 5

Absorption of water and toxins

Question 6

Kaolin & Pectin side effects and contraindications?

Answer 6

Digestion by bacteria leading to flatus

Question 7

Somatostatin like peptides drugs?

Answer 7

Octreotide

Question 8

Somatostatin like peptides mechanism of action?

Answer 8

Increase intestinal transit time by decreasing motility and release of other hormones

Question 9

Somatostatin like peptides side effects and contraindications?

Answer 9

• Steatorrhea and malabsorption
• Nausea, flatulence, abdominal pain
• Gallstones

Question 10

Resins drugs?

Answer 10

• Cholestyramine, Colestipol

Question 11

Resins mechanism of action?

Answer 11

• Modulates diarrhoea due to bile salt malabsorption

Question 12

Resins side effects and contraindications?

Answer 12

Malabsorption, GIT disturbances

Question 13

Lysophilizate mechanism of action?

Answer 13

Colonize colon and outcompete other pathogen

Question 14

Lysophilizate side effects and contraindications?

Answer 14

Lactose intolerance