Anti-Arryhthmic Drugs Flashcards
Most common type of arrythmia.
Atrial fibrillation (AFib)
Class I anti-arrhythmic drugs
Procainamide
Lidocaine
Flecainide
What do class I anti-arrhythmic drugs block?
Na+ Channels
What do class II anti-arrhythmic drugs block?
Beta receptors
What do class III anti-arrhythmic drugs block?
K+ Channels
Example of class II anti-arrhythmic drug
Metoprolol
Example of a class III anti-arrhythmic drug
Amiodarone
Slow response tissues in the heart.
SA and AV node
This part of the heart displays automaticity, allowing it to spontaneously depolarize.
SA Node
P wave
Atria depolarize
QRS Complex
Ventricles depolarize
T wave
Ventricles repolarize
QT Interval
The entire period of ventricular de and re-polarization
ST Interval
The period during which the ventricles are depolarized
Name of the current and phase that causes depolarization of SA node cells.
Pacemaker Current/ Phase 4
What occurs during phase 4?
Inward flow of Na (mostly) and Calcium
What occurs during phase 0?
Depolarization causes voltage-gated Calcium channels to open and Calcium rushes into the cells.
At what phase of the pacemaker action potential do the Calcium channels close and the potassium channels open for the membrane to repolarize?
Phase 3
In the SA nodal cells, it’s ________ that causes depolarization, this is important!
CALCIUM
Which phase has a brief initial repolarization (K+ outflow).
Phase 1
Phase 2
Inward Calcium and Outward Potassium
The SA nodal membrane repolarizes during this phase (less Calcium input, and Potassium output predominates).
Phase 3