Anti-arrhythmic drugs Flashcards
Quinidine
1a Na+ channel blocker
Procainamide
1a Na+ channel blocker
Disopyramide
1a Na+ channel blocker
1a sodium channel blockers MOA
decrease Vmax
increase APD
Quinidine MOA
Anticholinergic
alpha blocking: vasodilation & reflex tachycardia
Quinidine side effects
increase QT interval (tornadoes de pointes)
thrombocytopenia
cinchonism: tinnitus, hearing loss, GI upset, diplopia
Quinidine drug interaction
with antacids
increase quinidine absorption
Procainamide side effects
Agranulocytosis
SLE like syndrome
Disopyramide
most anticholinergic
Lidocaine
Tocainide
Mexiletine
1b Na+ channel blocker
1c Na+ channel blocker
Flecainide
propafenone
moricizine
1c Na+ channel blocker
Pro-arryhthmetic
BB use
prophylaxis post MI
SVT treatment
K+ channel blocker
increase APD
K+ channel blocker
Amiodarone Ibutilide Dofetilide Dronaderone Sotalol