Anti Alzeimer's Drugs

Question 1

Anti alzeimer drugs
1-
2-
3-
4-
5-

Answer 1

Donepezil
Galantamine
Memantine
Rivastagmine
Tacrine

Question 2

Acetycholinesterase inhibitors
1-
2-
3-
Reversible?

Answer 2

Donepezil
Galantamine
Rivastigmine
Yessss

Question 3

T or F
Galantamine is uncompettitive

Answer 3

False
All are uncompetitive except galantamine

Question 4

Common adverse effects of ACHI

Answer 4

Nausea diarrhea vomiting anorexia tremors brady muscle cramps

Question 5

NMDA receptoes is very important for —— and —– function

Answer 5

Synaptic plastictiy
Memory function

Question 6

NMDA antagonist
Name
Partial or complete blockage
Usages

Answer 6

Memantine (EBIXA)
Partial so that no toxic amountd of Ca2+ could enter
Slows the rate of memory loss in alzheimer’s dementia in patients with moderate to severe congnitive losses

Question 7

Drugs used in amyotrophic lateral sclerosis (maladie de charcot)
Class
Name
Usage

Answer 7

NMDA antagonist
Riluzole(Rilutek) blocks glutamate sodium and clacium channels
Improve the survival time and delay the need for ventilator support in patients suffering from ALS