antenatal screening Flashcards

1
Q

define screening

A

Screening is a process of identifying apparently healthy people who may be at increased risk of a disease or condition

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2
Q

why do we screen three main points

A

Identify high risk group for diagnostic testing
• Counsel about risk of disease being present
• Offer treatment or prevention

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3
Q

what are the drawbacks of screening

A

false positives and negatives
harm from screening or further testing
cost

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4
Q

to screen for disease what does the disease have to be like, it’s characteristics

A

have a detectable latent or early phase, must be an important health condition, an acceptable treatment exists

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5
Q

what is the criteria for a good screening test for a disease

A
  1. Valid and reliable
  2. Acceptable to population
  3. Cost is proportionate to medical care as a whole
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6
Q

who is offered screening for sickle cell anaemia and thalassaemia

A

in high incidence population everyone, in low incidence population ethnic minority

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7
Q

when does screening for sickle cell and thalassaemia occur and how is it performed

A

blood test and pre conception to ten weeks

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8
Q

if screening test is positive for sickle cell thalassaemia what do you do next

A

test partner, or prenatal diagnosis, amniocentesis

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9
Q

what do you do if screening shows baby has sickle cell or thalassaemia

A

early specialist care, termination

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10
Q

what infectious diseases are screened for in pregnant women and baby

A

HIV HEPB SYPHILLIS

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11
Q

how gets screened for infectious disease when pregnant

A

all women

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12
Q

how is screening for infectious disease done

A

serology (looking in serum for antibodies)

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13
Q

if pregnant mother test positive for syphilis what do you do

A

maternal treatment to prevent child transmission

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14
Q

if pregnant mother test positive for hiv what do you do

A

Maternal treatment • High risk antenatal care • Prevent transmission to neonate

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15
Q

if pregnant mother test positive for hep b what do you do

A

Changes antenatal care prevent transmission • Neonate receives vaccine

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16
Q

how do you screen for trisomy 21

A
  • Combined test
  • Fetal nuchal translucency
  • Maternal serum βHCG
  • Maternal serum PAPP_A
17
Q

when are mother screened for tri 21

A

Between 11+0-13+6 weeks gestation by ultrasound

18
Q

List fetal anomalies that can be detected by ultrasound(not limited to)

A

Brain • Acrania • Holoprosencephaly
Abnormalities that can be detected by ultrasound
• Spine • Open spina bifida • Face • Facial cleft • Anopthalmia • Neck • Cystic hygroma • Thorax • Congenital diaphragmatic hernia
• Abdominal Wall • Exomphalos • Gastroschisis • Urinary tract • Bilateral renal agenesis • Urethral obstruction • Extremities • Club foot • Arthrogryposis • Skeleton • Skeletal Dysplasia • Achondroplasia