Antenatal Care and Screening Flashcards

1
Q

What are the problems with morning sickness?

A
  • It affects around 80-85%
  • Worse when HCG levels are higher e.g. twins, molar pregancy
  • Can progress to hyperemesis gravidarum
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2
Q

What happens to cardiac output and HR in pregnancy?

A

CO increases by 30-50%
HR increases
Palpitations are common

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3
Q

What happens to blood pressure in pregnancy and why?

A

It drops in the second trimester (expansion of the uteroplacental circulation, a fall in systemic vascular resistance, reduction in blood viscocity and a reduction in sensitivity to angiotensin)
BP usually returns to normal in the third trimester

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4
Q

What happens to urine output in pregnancy and why?

A

Urine output is increased: renal plasma flow increases by 25-50%, GFR increases by 50% and serum urea/creatinine decrease

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5
Q

Why is there an increased risk of infection and pyelonephritis in pregnancy?

A

There is an increase in urinary stasis. Hydronephrosis is physiological in the 3rd trimester (makes pyelonephritis more common)
Can be associated with preterm labour

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6
Q

What is the reason for anaemia in pregnancy?

A

Plasma volume increases by roughly 50% and the RBC mass by 25% which results in a drop in haemaglobin. Iron requirements increase by 1g during pregnancy. WBCs also increase slightly and platelet count falls by dilution

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7
Q

What happens to respiration in pregnancy?

A
  • Progesterone acts centrally to reduce CO2
  • Tidal volume, resp. rate and plasma pH all increase
  • O2 consumption increases by 20%
  • Plasma PO2 is unchanged
  • Hyperaemia of resp. mucus membranes
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8
Q

What happens to the GI system in pregnancy?

A

Oesophageal peristalsis is reduced, gastric emptying slows, cardiac sphincter relaxes and GI motility is reduced (caused by progesterone and motilin)

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9
Q

What are the components of pre-pregnancy counselling?

A

General health measures: improve diet, optimise BMI and reduce alcohol consumption
Smoking cessation advice
Folic acid (400mcg)
Known medical problems/current medication/possibly advise against pregnancy
Previous pregnancy problems

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10
Q

What does an antenatal exam consist of?

A

Routine Enquiry: feeling well and feeling fetal movements (after 20wks)
BP and urinalysis
Abdominal Palpations: assess symphyseal fundal height, fetal presentation, estimate size of baby, estimate liquor volume and listen to the fetal heart

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11
Q

Which infections are pregnant women screened for?

A

HepB, syphilis, HIV, rubella and UTIs

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12
Q

What does the 1st ultrasound show?

A

Viable pregnancy
Multiple pregnancy
Abnormalities incompatible with life
Down’s Syndrome screening is also offered

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13
Q

What can be seen on a detailed anomaly scan?

A

Systematic structural review of the baby

Some problems that need intrauterine or postnatal treatment

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14
Q

What are the risk factors for Downs Syndrome?

A

Extremities of maternal age and personal/FH history of chromosomal abnormality

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15
Q

What is tested in 1st trimester trisomy screening?

A

Serum B-hCG, PAPP-A and fetal nuchal translucency measurement

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16
Q

What happens when there is a high risk result from downs syndrome screening?

A

Further testing is offered: CVS, amniocentesis and non-invasive prenatal testing

17
Q

What is involved in non-invasive prenatal testing?

A
  • Maternal blood is taken
  • Fetal cell free DNA can be detected
  • Chromosomal trisomies can be looked for
  • Not offered on the NHS
  • If there is high risk, invasive testing is recommended to confirm
18
Q

What is involved in screening for neural tube defect?

A
  • Personal/FH of NTD - advised to take folic acid supplements
  • First trimester USS for ancephaly and spina bifida
  • Second trimester biochemical screening (alpha fetoprotein)
  • Second trimester USS will detect >90% of NTD
19
Q

Which structural defects can be detected on a 2nd trimester USS?

A

Hypoplastic left heart, exomphalos and cleft lip (these are only a few examples)