Antacids, PPIs and H2 Receptor Antagonists Flashcards
Which metal antacid causes a laxative effect
Magnesium
Which metal antacid causes constipation
Aluminum
Which metal antacid induces rebound acid secretion
Calcium
What does Simeticone (anti-foaming agent) do
relieve flatulence
What is the mechanism of action of Antacids
forms viscous raft on top of stomach contents
Why should you not take enteric coated capsules when taking Antacids
because antacids increase stomach pH
—-> breaking down enteric coating too quick
What is the interaction between Lithium + Antacids causes
Hypernatraemia
Which condition, when taking antacids, causes hypernatreamia
Hypertension
What medication taken with antacids causes Hypernatraemia
Lithium
What happens when Antacids are taken in hypertension
Hypernatraemia
Which drugs should you not take with Antacids and why
- Bisphosphonates
- Tetracyclines
- Ciprofloxacin
because antacids reduce absorption
What is the MHRA warning for PPI
risk of subacute cutaneous lupus erythromatosus
what is subacute cutaneous lupus erythromatosus
autoimmune disease where body attacks heathy cells
What do PPIs increase the risk of
- Fractures
- C.Diff
Why do PPIs increase the risk of fractures
due to hypomagnaesia
