ant pituitary hormones

Question 1

Growth hormone (GH) preparations

Answer 1

1. Recombinant human GH
   * Somatropin
   * Somatrem
2. Insulin-like growth factor -1 (IGF-1) preparation
   * Mecasermin

Question 2

Growth hormone release inhibitors

Answer 2

1. Somatostatin
2. Octreotide
3. Lanreotide

Question 3

gonadotropin prep

Answer 3

1. Menotropins (FSH + LH)
2. Menotropin (pure FSH)
3. Urofollitropin (uFSH)
4. Follitropin-α & follitropin-β (recombinant forms of FSH)
5. Choriogonadotropin-α (recombinant HCG)
6. Lutropin-α (recombinant human LH)

Question 4

GnRH agonist

Answer 4

1. Leuprolide
2. Nafarelin
3. Buserelin
4. Goserelin

Question 5

Rational for combination

Answer 5

The concurrent use of androgen receptor antagonists like flutamide/ bicalutamide with GnRH agonists block effect of testosterone on cancer cells and prevent “flare-up” of symptoms of prostatic carcinoma.