ANS Pharmacology

Question 1

Prazosin

Answer 1

Alpha-1 antagonist (decreases NE effect)

Question 2

Phenylephrine

Answer 2

Alpha 1 agonist (increases NE effect)

Question 3

Clonidine

Answer 3

Alpha 2 agonist (decreases NE effect thru neg feedback)

Question 4

Pseudoephedrine

Answer 4

Indirect agonist - increase NE transmission.
Useful for nasal congestions (vasoconstriction).

Question 5

Phenoxybenzamine

Answer 5

Used in pheochromocytomas.

Alpha adrenergic receptor irreversible blocker

Question 6

Propanolol

Answer 6

Prototype beta blocker, blocks beta 1 & 2 adrenergic receptors (antagonist).

Question 7

Cocaine effect on Epi and NE

Answer 7

Blocks transmitter reuptake - increase in BP

Question 8

Amphetamine effect on Epi and NE

Answer 8

Indirect agonists, increase release of NE.

Question 9

Beta 1 receptors characteristics

Answer 9

Heart cells.
NE >Epi

Question 10

Beta 2 receptors characteristics

Answer 10

Bronchial smooth muscle.
Epi >NE

Question 11

Mean arterial pressure equation

Answer 11

MAP = Heart rate x stroke volume x PVR x