ANS Basics Flashcards
Cholinergic Neurons
Release Ach
Adrenergic Neurons
Release NE
AcH Removal from Synapse
Degradation/metabolism
NE removal from synapse
Diffusion
Re-uptake and metabolism
Presynaptic Sympathetic Neurotransmitter
Ach
Presynaptic Parasympathetic Neurotransmitter
Ach
Postsynaptic Sympathetic Neurotransmitter
Usually NE
Postsynaptic Parasympathetic Neurotransmitter
Ach
Postsynaptic sympathetic receptors
Nicotinic (Nn) Ach receptors
Postsynaptic parasympathetic receptors
Nicotinic (Nn) Ach receptors
Target organ parasympathetic receptors
Muscarinic Ach receptors
Target organ sympathetic receptors
Alpha or beta adrenergic receptors
Organs receiving only sympathetic innervation
Skin, sweat glands, smooth muscle of blood vessels
Sympathetic innervation of the eye
ciliary muscle relaxes, pupils dilate
Parasympathetic innervation of the eye
Ciliary muscle contracts, pupils constrict CN III
Sympathetic innervation of the heart
Beta 1 and 2 receptors
Increase contractility and HR
Parasympathetic innervation of the heart
Muscarinic type 2 receptors
Decrease contractility and HR
Sympathetic innervation of the blood vessels
Alpha 1 receptors
Vasoconstriction of vessels in skin and splanchnic vessels
Beta 2 receptors
Skeletal muscle blood vessel dilation
Parasympathetic innervation of the bronchiole smooth muscles
Muscarinic receptors
Constriction
Sympathetic innervation of bronchiole smooth muscle
Beta 2 receptors
Relaxation/dilation
Sympathetic innervation of the GI tract
Alpha 1 receptors
Contracts sphincters
Alpha 2 receptors
Relax smooth muscle of vessel walls (decrease tone)
Parasympathetic innervation of the GI Tract
Muscarinic Receptors
Increase motility by contracting smooth muscle of vessel walls, relax sphincters
Sympathetic innervation of the GU system
Beta 2 Receptors
Relax bladder wall
Alpha 1 receptors
Contract Sphincters
Parasympathetic Innervation of the GU system
Muscarinic receptors
Contract bladder wall, relax sphincters
Sympathetic innervation of the skin
Alpha 1 receptors
Contraction of pilomotor smooth muscle, sweat gland secretion