ANS Flashcards

1
Q

AntiCholinergic tox

A
  1. Hot as hare
  2. Blind as bat
  3. Mad as hatter
  4. Dry as bone
  5. Full as flask
  6. Flushed as beet
  7. Fast as fiddle
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2
Q

PANS

NT:
f

A
  • Visceral (f)
  • pre-gang neurons : CN III, VII, IX, X + sacral SC » ACh — post-gang in parasymp ganglia » Muscarinic receptors

Pre+post both release ACh

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3
Q

SANS:

(f):
NT:

A
  • thoracolumbar pre-gang » ACh — post-gang neurons in prevertebral ganglia » NE - alpha/beta receptors

EXCEPT

  1. Adrenal medulla directly releases Epi + NE
  2. Swear glans pre+post both release ACh
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4
Q

Somatic

A

ACh + N to skeletal muscle

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5
Q

M1

  1. (f)
  2. Inhibition
A

Brain - memory/ cognition

Confusion

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6
Q

M2 (f)

A

Heart

Dec HR + atrial contractions

Gi

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7
Q

M3 (f)

A

Periph vasc x Sm relaxation, vasodilation, dec BP

Lungs - bronchoconstriction

Bladder - detrusor contraction

Eyes - miosis, ciliary contraction (accommodation)

GI - inc peristalsis, salivary + gastric secretion

Skin - inc sweat

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8
Q

What receptors on endoth cells promote smooth muscle relaxaton?

A

M3

  • inc NO
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9
Q

Which drugs have anticholinergic activity?

A

FG antihistamines

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