Angiotensin II Receptor Blockers Flashcards
1
Q
The ARBs all end in
A
“sartan” VILT.. Valsartan, Irbesartan, Losartan, Telmisartan
2
Q
Do the ARBs block angiotensin I or angiotensin II receptors?
A
They block angiotensin II receptors
3
Q
Do ARBs effect bradykinin?
A
No, they are a good substitute for ACEI when the ACEI cause a cough
4
Q
This ARB is a prodrug with one of its metabolites being a angiotensin I receptor agonist
A
Losartan
5
Q
This ARB inhibits platelet aggregation
A
Losartan
6
Q
This ARB increases uric acid urinary excretion
A
Losartan
7
Q
This ARB inhibits CYP activity
A
Losartan
8
Q
Side effects of ARBs
A
hypotension, hyperkalemia, hepatic dysfunction, fetotoxicity