ANESTHESIA: INTRODUCTION AND HISTORY Flashcards
What plant did Dioscorides associate with narcotic-like effects in the first century A.D.?
Mandragora
What did Bailey’s An Universal Etymological English Dictionary (1721) define anesthesia as?
A defect of sensation
How did the 1771 Encyclopedia Britannica define anesthesia?
Privation of the senses
Who first proposed the modern use of the term ‘anesthesia’ in 1846?
Oliver Wendell Holmes
What are the key components of anesthesia as proposed by Oliver Wendell Holmes?
Amnesia, analgesia, and narcosis
What is included in the preoperative evaluation and assessment in anesthesiology?
Assessment, consultation, and preparation of patients for anesthesia
What is the role of anesthesiologists during surgical, obstetric, therapeutic, and diagnostic procedures?
Relief and prevention of pain
What is the anesthesiologist’s responsibility during a procedure?
Monitoring and maintaining normal physiology
Who are the intensivists among medical professionals?
Anesthesiologists
What pain types do anesthesiologists diagnose and treat?
Acute, chronic, and cancer-related pain
What areas of care are anesthesiologists involved in besides surgery?
Hospice, palliative care, and critical care
What historical substances were used by ancient Egyptians for premedication?
Opium poppy (morphine) and hyoscyamus (scopolamine)
What did Incan surgeons use as local anesthesia in the 1500s?
Coca leaves chewed and spat onto the operative site
What is an example of a depolarizing neuromuscular blocking agent?
Succinylcholine
Who prepared ether for the first time in 1540?
Valerius Cordus
Who used ether as an anesthetic in humans in 1842?
Crawford W. Long and William E. Clark
When is World Anesthesia Day celebrated?
October 16
Who conducted the first publicized demonstration of ether?
William Thomas Green Morton
Who prepared chloroform around 1831?
Moldenhawer, Von Liebig, Guthrie, and Soubeiran
Who introduced chloroform into clinical practice to relieve labor pains?
Sir James Simpson
Why was chloroform eventually abandoned?
It caused cardiac arrhythmias, respiratory depression, and hepatotoxicity
Who produced nitrous oxide in 1772?
Joseph Priestley
Who first noted the analgesic properties of nitrous oxide in 1800?
Humphry Davy
Who used nitrous oxide for dental procedures in 1844?
Gardner Colton and Horace Wells
Why was nitrous oxide initially less popular than ether or chloroform?
Low potency and risk of asphyxiation
Who popularized the use of chloroform during Queen Victoria’s childbirth?
John Snow
What is John Snow recognized for apart from anesthesiology?
Tracing the source of a cholera outbreak in Soho, England, in 1854
What anesthetic rivaled ether after being introduced in 1934?
Cyclopropane
What year marked the introduction of halothane, the first non-flammable potent fluorinated hydrocarbon?
1956
Which inhalation anesthetic requires a special vaporizer due to environmental concerns?
Desflurane
What are the primary inhalation anesthetics available in the Philippines today?
Sevoflurane and isoflurane
What is the significance of MAC (minimum alveolar concentration) in inhalational anesthesia?
It is the concentration at which 50% of patients will not feel pain or a surgical incision
Who introduced modern local anesthesia using topical cocaine in 1884?
Carl Koller
Who isolated cocaine from the coca plant in 1855?
Gaedicke
Who purified cocaine in 1860?
Albert Niemann
Who demonstrated the use of cocaine in intradermal infiltrations and nerve blocks?
William Halsted
Who administered the first spinal anesthetic in 1898?
August Bier
What is the Bier Block, introduced by August Bier in 1908?
An intravenous regional anesthesia technique
Who synthesized procaine in 1904?
Alfred Einhorn