Anemia Quiz row 5,6,7

Question 1

Megaloblastic Anemia

Causes

Answer 1

1. dietary deficiency of B12 or folate
2. increased physiologic need
3. malabsorption
4. pernicious anemia (lack of IF)

Question 2

Megaloblastic Anemia

MCV, MCHC, RDW

Answer 2

• MCV = increased
• MCHC = normal
• RDW = increased

Question 3

Megaloblastic Anemia

Morphology

Answer 3

• macrocytes
• elliptocytes
• howell jolly bodies

Question 4

Megaloblastic Anemia

Tests

Answer 4

• B12 deficiency
  
  • serum B12 = decreased
  • folate = normal
• foalte deficiency
  
  • serum B12 = normal
  • folate = decreased

Question 5

Aplastic Anemia

Causes

Answer 5

1. Autoimmune destruction
2. exposure to chemicals, drugs, or radiation
3. inherited

Question 6

Aplastic Anemia

MCV, MCHC, RDW

Answer 6

• MCV = normal
• MCHC = normal
• RDW = normal

Question 7

Aplastic Anemia

Morphology

Answer 7

• mild anisocytosis
• poikilocytosis

Question 8

Aplastic Anemia

Tests

Answer 8

• Bone marrow
  
  • <25% cellularity
  • <0.5x10^9/L granulocytes
  • <20x10^9/L platelets
  • <1% reticulocytes

Question 9

Hemolytic Anemia

Causes

Answer 9

1. membrane defect
2. enzyme defect
3. immune mediated

Question 10

Hemolytic Anemia

MCV, MCHC, RDW

Answer 10

• MCV = normal
• MCHC = normal
• RDW = increased

Question 11

Hemolytic Anemia

Morphology

Answer 11

• Polychromasia
• NRBCs

Question 12

Hemolytic Anemia

Tests

Answer 12

• Reticulocytes = increased
• unconjugated bilirubin = increased
• haptoglobin = decreased