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Hematology > Anemia aplastica > Flashcards

Anemia aplastica Flashcards

1
Q

Factori etio

A 
b genetica
subst ch mielosupresive/toxice
radiatii
infectii
b clonale
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2
Q

Patogenie

A 
anomalii cant - depletie CS
anomalii calit - scaderea capacit de autoreinnoire, perturb ech autoreinnoire-dif
supresie imuna umorala/cel/citokine
anomalii micromediu
deficit fact de crestere hematopoietici
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3
Q

Hlg

A

PANCITOPENIE
anemie normo/normo, ret scazute
leucopenie, granulopenie
trombocitopenie

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4
Q

Medulograma

A

saraca
serii mieloife diminuate/absente
infiltrat Ly, Pl, Mfg

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5
Q

BOM

A

hipocel
insule rest de hematopoieza
exsudat fibros, fb retic ingros
infiltrat Ly, Pl, Mfg

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6
Q

Severitate medie

A

G <1000
PLT <50.000
Ret < 60.000
Hb < 10 g/dl

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7
Q

AA severa

A

G <500
PLT < 20.000
ret < 10.000
MO aplazica

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8
Q

AA f severa

A

G < 200 (agranulocitoza)

PLT < 20.000

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9
Q

Tratament AA medie

A

imunosupresie, androgeni, f crest hematopoietici

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10
Q

Tratament AA severa si f severa

A

transplant medular + imunosupresie

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Hematology (12 decks)

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