Androgens Flashcards
0
Q
oxandrolone and nandrolone are both ………….
A
androgens
1
Q
areas of use?
A
- hypogonadism e.g Klinefelter
- illicit use in body building
2
Q
Androgens side effects?
A
- maculinization
- premature closure of epiphysis
- cholestatic jaundice(cholesterol based –> biliary excretion)
- aggression
- dependence
3
Q
Two main reasons to block androgens?
A
cancer
BPH
4
Q
Flutamide and Leuprolide are both ……..
A
androgen antagonists
5
Q
Finasteride moa?
A
inhibits 5-alpha reductase which prevents conversion of testosterone to dihydrotestoterone
6
Q
Dihydrotestosterone have these two pristine effects on the male body?
A
baldness and prostate enlargement
7
Q
Finasteride side effects?
A
teratogenicity if woman is exposed
