Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CRRAB--Wk 3 > Androgenic Agonists--Trachte > Flashcards

Androgenic Agonists--Trachte Flashcards

1
Q

Synthesis of catacholamines

A

tyrosine –> DOPA

tyrosine hydroxylase

DOPA –> dopamine

DOPA decarboxylase

dopamine –> NE

dopamine hydroxylase

NE –> Epi

Phenyl-N-methyltransferase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Function of nAChR

A

Na+ channel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Parglyline

A

MOA: MAO inhibitor

TU: potentiates sympathetic responses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Cocaine

A

MOA: axoplasmic reuptake inhibitor

TU: local anesthesia

Adverse: do not give β1 blockers when cocaine intoxication, can lead to unopposed HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Imipramine

A

MOA: axoplasmic reuptake inhibitor

TU: antidepressant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tyramine

A

MOA: axoplasmic reuptake pump reversal

Adverse: can cause hypertensive crisis

Found in: wine, cheese, beer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Amphetamine

A

MOA: axoplasmic reuptake reversal

TU: narcolepsy, obesity , ADD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ephedrine

A

MOA: releases stores catecholamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Reserpine

A

MOA: blocks vesicular accumulation, depletes NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Guanethidine

A

MOA: releases NE from vesicles, depletes NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dobutamine

A

MOA: β1 agonist

TU: CHF or MI w/ acute heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dopamine

A

MOA: β1 agonist at low doses

α1 agonist at high doses

TU: shock, heart failure, unstable bradycardia, ionotropic and chronotropic α effects, maintains renal perfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Phenylephrine

A

MOA: α1 agonist

TU: eye exams (mydriatic), hyptension, rhinitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Metaproterenol

A

MOA: β2 agonist

TU: asthma

Adverse: tremor, palpitations, tachycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Albuterol

A

MOA: β2 agonist

TU: asthma

Adverse: tremor, palpitations, tachycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Salmeterol

A

MOA: β2 agonist

TU: asthma

Adverse: tremor, palpitations, tachycardia

17
Q

Ritodrine

A

MOA: β2 agonist in uterus

TU: delay labor

Adverse: tremor, palpitaitons, tachycardia

18
Q

Isoproterenol

A

MOA: β2 > β1 agonist –> hypotensive tachycardia

TU: cardiac stimulant

19
Q

NE

A

MOA: α1 and β1 agonist

TU: hypotension

Contra: pregnancy, anesthesia, hyperthyroidism

20
Q

Epinephrine

A

MOA: α1 vascoconstriction, β1 tachycardia, β2 vasodilation (limited)

TU: allergic rxns, increased BP (α1), bronchodilation (β2)

Contra: hyperthyroidism, HTN, halogenated-hydrocarbon anesthetics (vasoconstriction prevents adequate perfusion)

CRRAB--Wk 3 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions