Ancef

Question 1

Cefazdin/Ancef: mechanism of action and indications

pregnancy

Answer 1

Classification: 1st generation cephalosporins

MOA: inhibitors of cell wall synthesis

indications: First-generation cephalosporins have coverage against most gram-positive cocci as well as some gram-negative bacteria, e.g., Escherichia coli (E. coli), Proteus mirabilis, and Klebsiella pneumoniae. Used with gram + infection; surgical prophylaxis, and with MILD PCN allergy

pregnancy classification: unsure–no data but does cross the placental barrier

Question 2

Cefazdin/Ancef:

FDI, labs, nursing assessment, method of administration, education

Answer 2

fdi: High Blood Pressure (Hypertension)
Moderate Potential Hazard, High plausibility
Parenteral cefazolin sodium contains approximately 46 mg (2 mEq) of sodium per each gram of cefazolin activity. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention.

lab tests: 
nursing assessment (pre admin): assess for penicillin allergy 

nursing assessment (post admin): asses for allergy and severe side effects (including HTN) dc and find another med if side effects shown

method of administration: IM or IV

patient and family education: complete whole course, do not miss a dose

Question 3

Cefazdin/Ancef

side effects

Answer 3

Common:
nausea, vomiting, diarrhea;
rash; or
an allergic reaction.

Severe:
severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
white patches or sores inside your mouth or on your lips;
fever, swollen glands, rash or itching, joint pain, or general ill feeling;
seizure (convulsions); or
liver problems–upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).