Anatomy & Physiology Flashcards
Anatomy
The science of the structure of the body and the relation of its parts
Physiology
The science of how the body functions
Prokaryote
Cell lacks true membrane bound nucleus and organelles
What type of cell are all bacteria?
Prokaryote
Eukaryote
Has membrane bound nucleus and organelles
Three major components to eukaryotes
Cell membrane
Nucleus
Cytoplasm
What are cell membranes composed of
Double layer phospholipids
Proteins
Carbohydrate chains
Cholesterol
Components of ribosomes
Proteins
RNA
Ribosome function
Protein synthesis
What types of cells have large numbers of mitochondria
Cells that require high levels of energy
Rough endoplasmic reticulum function
Protein transport
Smooth endoplasmic reticulum function
Cholesterol synthesis Steroid hormone synthesis Lipid synthesis Drug detoxification Glycogen breakdown Fat transport
Where are large amounts of smooth endoplasmic reticulum
Liver cells
Intestinal cells
Testes
Golgi Complex Function
Receiving, packaging, distribution
Modify & synthesize carbohydrate portion of glycoproteins
Export substances from endoplasmic reticulum to cytoplasm
Lysosome production
Lysosome functions
Digestive enzymes for intracellular bacteria
Breakdown nonfunctional organelles
Where are large numbers of lysosomes found
Phagocytic cells
What are peroxisomes
Membrane bound organelles that contain strong oxidase and catalase enzymes
Peroxisome functions
Detoxify alcohol & formaldehyde
Convert free radicals into peroxide
Where are large numbers of peroxisomes found
Liver cells
Kidney cells
Function of cytoskeleton
Form / structure
Support
Enables movement
Centrioles
Base of cilia and flagella
Solute
Substance that can be dissolved
Solvent
Substance that does the dissolving
Solution
Uniform mixture of solute and solvent
Intercellular
Between cells / interstitial
Types of passive transport
Diffusion
Facilitated diffusion
Osmosis
Filtration
Diffusion
Movement of molecules from areas of high concentration to areas of low concentration
Example of diffusion
Oxygen / CO2 exchange
Facilitated Diffusion
Diffusion with the aid of a carrier protein
Example of facilitated diffusion
Glucose entering cells
Osmosis
Movement of water from area of low solute concentration to area of high solute concentration
Osmotic Pressure
Amount of pressure needed to stop flow of water across a membrane
Filtration
Small solutes being forced through a membrane by hydrostatic pressure
What kind of passive transport is used in the kidneys
Filtration
Types of active transport
Endocytosis
Exocytosis
Active transport
Endocytosis
Materials being taken into a cell
Types of Endocytosis
Phagocytosis
Pinocytosis
Receptor-mediated
Phagocytosis
Cell eating
Cell membrane extends around solid particles
What types of cells perform phagocytosis
Some WBC
Macrophages
Pinocytosis
Cell drinking
Cell membrane extends around fluid droplets
What cells perform pinocytosis
Absorptive cells in the small intestine
Receptor-Mediated Endocytosis
Specialized membrane receptors bind to substances entering the cell
What types of substances enter the cell through receptor-mediated endocytosis
Enzymes Insulin Hormones Iron Cholesterol
Exocytosis
Materials expelled by the cell
What types of substances utilize exocytosis
Hormones
Neurotransmitters
Waste materials / mucus
Active Transport
Movement of molecules from areas of low concentration to areas of high concentration with the aid of carrier proteins
What types of substances use active transport
Sodium potassium pump
Ions
Amino acids
Hypotonic
Extracellular fluid less concentrated than intracellular fluid
What happens to RBC in hypotonic solutions?
Gain water & burst
Hemolysis
Hypertonic
Extracellular fluid is more concentrated than intracellular fluid
What happens to RBC in hypertonic fluid?
Lose water and shrivel / crenate
Isotonic
Concentrations of extracellular and intracellular fluids are equal
Tissue
Groups of similar cells with related functions
Histology / Microanatomy
Study of tissues
Four primary types of tissue
Epithelial
Connective
Muscle
Nervous
Subtypes of epithelial tissue (6)
Squamous Cell Cuboidal Columnar Pseudostratified columnar Transitional Glandular
Squamous Epithelium characteristics
Flat, thin, plate-like cells
Where are simple squamous epithelial cells found
Lines blood vessels
Alveoli of lungs
Thoracic cavity
Abdominal cavity
Where are stratified squamous epithelial cells found
Areas of wear Mouth Esophagus Vagina Rectum Epidermis (keritinized)
Cuboidal Epithelium characteristics
Cube-shaped cells
Where are simple cuboidal epithelial cells found
Glands
Ducts
Surface of ovary
Kidney tubules
Where are stratified cuboidal epithelial cells found
Fairly rare
Lines sweat ducts
Salivary glands
Mammary glands
Columnar Epithelium characteristics
Tall, rectangular cells
Where are simple columnar epithelial cells found
Lines digestive tract
Bronchi
Uterine tubes
Uterus
Where are stratified columnar epithelial cells found
Relatively rare
Mammary ducts
Portions of male urethra
Pseudostratified Columnar Epithelium characteristics
Appear to be more than one layer but all cells contact basal membrane
Usually ciliated
Associated with goblet cells
Where are pseudostratified columnar epithelial cells found
Respiratory tract
Transitional epithelium characteristics
Resemble cuboidal & squamous shaves
Where are transitional epithelial cells found
Areas needing great distension
Urinary bladder
Ureters
Part of urethra
Glandular epithelium characteristics
Specialized to secrete
Where are glandular epithelial cells found
Ducts
Endocrine Glands
Ductless
Secrete hormones directly into the bloodstream
Exocrine Glands
Have ducts and secrete onto an epithelial surface
Elements of connective tissue (3)
Cells
Fibers
Matrix
Functions of connective tissue
Connects stuff Structural support Protection Insulation Transports fluids Stores energy
Types of fibers / connective tissue fibers (3)
Collagen fibers
Elastic fibers
Reticular fibers
Collagen fibers
Long, straight, very strong
White
Composed of collagen
Elastic Fibers
Long, thin, branching, stretchable
Yellow fibers composed of elastin
Reticular Fibers
Collagen fibers in a complex network
Loose Connective Tissue Types
Areolar
Adipose
Reticular
Areolar tissue
Most widely distributed
Supports organs
Protection & flexibility
What types of cells are made of areolar tissue
Fibroblasts
Macrophages
Mast cells
WBC
Adipose Tissue
Insulation
Cushioning
Protection
Reserve energy
What types of cells make up adipose tissue
Adipocytes
Reticular tissue
Supportive
Where is reticular tissue found
Spleen
Liver
Lymph nodes
Bone marrow
What is reticular tissue made up of
Reticular fibers
macrophages
fibroblasts
Dense connective tissue types
Regular
Irregular
Elastic
Regular connective tissue examples
Tendons
Ligaments
Aponeuroses
What makes up regular connective tissue
Collagen fibers arranged in a parallel pattern
Fibroblasts provide strong attachments
Tendons
Connect bone to muscle
Ligament
Connect bone to bone
Aponeuroses
Connect muscle to muscle
Irregular connective tissue
Provide strength and support to areas experiencing force from all directions
Examples of irregular connective tissue
Dermis
Organ capsules
Joint capsules
Make up of irregular connective tissue
Collagen fibers arranged in an irregular pattern, elastic fibers, fibroblasts
Elastic Connective tissues
Ligaments that have a higher elastic fiber content than collagen content
Elastic connective tissue example
Equine nuchal ligament
Specialized cartilage types
Hyaline
Elastic
Fibrocartilage
Hyaline cartilage make up
Collagen fibers and chondrocytes
Examples of hyaline cartilage
Nose Trachea Larynx Embryonic skeleton Costal cartilage Articular cartilage
Elastic cartilage
Provides shape and great flexibility
Examples of elastic cartilage
Pinna
Auditory canal
Epiglottis
Elastic fibers
Fibrocartilage
Provides strong support
Examples of fibrocartilage
Intervertebral discs Pubic symphysis Disc in stifle Thick collagen fibers Chondrocytes
Types of membranes (3)
Mucous membranes
Serous membranes
Cutaneous membranes
Serous membranes
Line body cavities but do not connect the to the exterior world
Serous membrane characteristics
Simple squamous epithelium connected to loose connective tissue
Function of serous membranes
Reduce friction
Cutaneous membrane
Membrane exposed to the outside world
Characteristics of cutaneous membrane
Keratinized, stratified squamous epithelium
Attached to a layer of dense irregular connective tissue
Function of bones
Support soft tissues Protect vital organs Lever for muscle attachment Mineral storage Blood production
Types of bone (2)
Compact
Spongy
Compact bone
Provides strength and support
Very few spaces
Appears solid
Components to haversian system
Central haversian canal
Canaliculi
Lamellae
Lacunae
Central haversian canal
Houses blood vessels & nerves
Canaliculi
Very small canals in bone that radiate out and connect all lacunae to each other and haversian canal
Lamellae
Concentric rings of bone
Lacunae
Small spaces that house osteocytes / mature bone cells
Spongy bone
Large spaces of lattice-like bone / trabeculae filled with marrow
Diploe
Spongy bone of the skull
Appendicular skeleton
All bones in the limbs
Types of bone cells (3)
Osteoblast
Osteoclast
Osteocyte
Osteoblast
Immature bone cell
Produces bone matrix / osteoid
Osteocyte
Mature bone cell
Osteoclast
Very large, multinucleated cells that breakdown bone matrix
Classifications of bones (6)
Long bones Short bones Flat bones Pneumatic bones Irregular bones Sesamoid bones
Long bones
Diaphysis containing a marrow cavity with two epiphyses
Main supporting bones of the body
Articular cartilage
Hyaline cartilage that covers the ends of bones
Periosteum
Fibrous membrane that covers the outside of bones
Rich in blood, nerves, lymph vessels
Endosteum
Lines marrow cavity
Epiphyseal Cartilage
AKA growth plate
Region between epiphysis and diaphysis
Short bones
Two thin layers of compact bone with spongy bone between
Function of short bones
Shock absorption
Examples of short bones
Tarsus
Carpus
Flat bones
Two layers of compact bone with spongy bone between
Function of flat bones
Protection
Examples of flat bones
Pelvis
Scapula
Ribs
Many skull bones
Pneumatic bones
Contain sinuses
Play role in respiration in birds
Irregular bones
Unpaired bones with complicated shapes
Examples of irregular bones
Vertebra
Some skull bones
Sesamoid bones
Small short bones attached to tendons found near freely moving joints
Function of sesamoid bones
Reduce friction along a joint
Types of osteogenesis
Endochondral
Intramembranous
Endochondral osteogenesis
Formed from cartilage bars laid down in the embryo
What bones are formed via endochondral osteogenesis
Most bones
Intramembranous osteogenesis
Bones formed from fibrous membranes laid down in the embryo
What bones are formed via intramembranous osteogenesis
Most flat bones
Dog / Cat vertebral formula
C7, T13, L7, S3, C6-23
Horse vertebral formula
C7, T18, L6, S5, C15-20
Cattle vertebral formula
C7, T13, L6, S5, C18-20
Pig vertebral formula
C7, T14-15, L6-7, S4, C20-23
Sheep vertebral formula
C7, T13, L6-7, S4, C16-18
Joint / Articulation
When two or more bones are united by fibrous, elastic or cartilaginous tissue
Classifications of joints by function (3)
Synarthrosis
Amphiarthrosis
Diarthrosis
Synarthrosis
Immovable joint
Amphiarthrosis
Slightly moveable joint
Diarthrosis
Freely moveable joint
Types of synovial joints (6)
Ball & Socket / spheroid Arthrodial / condyloid Trochoid / pivot Hinge / ginglymus Gliding Saddle
Examples of ball and socket / spheroid joint
Hip
Shoulder
Examples of arthrodial / condyloid joint
Radiocarpal joints
Example of trochoid / pivot joint
Atlantoaxial joint
Example of hinge / ginglymus joint
Stifle
Elbow
Example of gliding joint
Radioulnar joint
Intervertebral joints
Example of saddle joint
In primates only
Carpometacarpal joint
Flexor
Decreases angle of a joint
Extensor
Increases the angle of a joint
Abductor
Moves bone away from midline
Adductor
Moves bone toward midline
Levator
Produces dorsally directed movement
Depressor
Produces ventrally directed movement
Sphincter
Decreases size of an opening
Parts of the brain (4)
Cerebrum
Diencephalon
Brainstem
Cerebellum
Cerebrum
Site of motor control, interpretation of sensory impulses and areas of association
Longitudinal fissure
Prominent groove dividing right and left hemispheres of the brain
Lobes of the cerebrum (4)
Frontal
Occipital
Temporal
Parietal
Parts of the brainstem (3)
Pons
Midbrain
Medulla oblongata
Midbrain
Connection between forebrain / cerebrum and hindbrain
Pons
Contains respiratory centers
Medulla oblongata
Where nerve fibers cross
What physiologic processes does the medulla influence
Respiratory rate Heart rate Vomiting Coughing Sneezing
Reticular Activating System
Responsible for sleep-wake cycles
Afferent
Nerve impulses from periphery to the brain / sensory nerves
Efferent
Nerve impulses from the vein to the periphery / motor nerves
Parts of meninges (5)
Dura mater Arachnoid mater Pia mater Epidural space Subarachnoid space
Dura mater
Outer layer of brain composed of dense, fibrous connective tissue
Arachnoid mater
Middle layer of the brain consisting of delicate and elastic connective tissue
Pia mater
Transparent
Connective tissue containing tiny blood vessels that adheres to the surface of the brain and spinal cord
Epidural space
Between the bone and dura mater
Loos connective tissue, blood vessels and fat
Subarachnoid space
Contains cerebrospinal fluid and large blood vessels
Function of cerebrospinal fluid
Cushion and nourish brain
Blood brain barrier
Protects brain from fluctuations in chemical levels
Peripheral nervous system divisions
Afferent
Efferent
Sympathetic nervous system
Fight or flight response
Parasympathetic nervous system
Returns body back to normal
What does the sympathetic nervous system release
Adrenergic neurotransmitter / norepinephrine
What does the parasympathetic nervous system release?
Cholinergic neurotransmitter / acetylcholine
Saltatory conduction
Transmission of a nerve impulse across a myelinated neuron
Neuroglial cells / Glial cells
Connective tissue cells that do not transmit impulses
Types of glial cells in CNS (4)
Astrocytes
Oligodendrocyte
Microglia
Ependymal
Astrocyte
Starshaped and most abundant, support nervous tissue and stimulate formation of blood brain barrier
Oligodendrocyte
Small cells that wrap around axons to form myelin sheath
Microglia
Phagocytic cells
Ependymal
Ciliated to help circulation of cerebrospinal fluid
Glial cells in PNS (2)
Schwann cells
Satellite cells
Swchwann Cells
Wrap around axons to form myelin in PNS
Comparable to oligodendrocytes
Satellite Cells
Surround cell bodies, function is unknown
Protective layers of the heart (2)
Pericardium
Endocardium
Pericardium
Double walled membranous sac covering the myocardium
Layers of the pericardium (2)
Fibrous pericardium
Serous pericardium
Layers to the serous pericardium
Parietal layer
Visceral layer
Endocardium
Serous membrane lining the inner chambers of the heart
Heart rate of dogs
60-160
Cat HR
140-220
Horse HR
28-50
Cow HR
40-80
Pig HR
70-120
Llama HR
60-90
Mouse HR
450-750
What does the P wave represent
Electrical events during atrial systole / depolarization
What does the QRS complex represent
Ventricle systole / depolarization
What does the T wave represent
Ventricular diastole / repolarization
Arteries
Carry oxygenated blood away from the heart, except pulmonary artery
Arterioles
Lead to and regulate blood flow to capillaries
Veins
Larger than arteries with thinner walls and valves to prevent backflow
Carry blood to heart
5 basic processes of GI to prepare food for utilization
Food ingestion Mechanical and chemical digestion Peristalsis Absorption Defecation
Layers of the GI wall (4)
Mucosa
Submucosa
Muscularis externa
Serosa
GI Mucosa layers (3)
Epithelium
Lamina propria
Muscularis mucosae
Larynx
Common passageway for digestive and respiratory systems
Regions of the stomach (4)
Esophageal
Cardiac
Fundic
Pyloric
Esophageal region of stomach
Nonglandular region
Cardiac region of stomach
Produces mucus
Fundic region of stomach
True body of the stomach, contains gastric glands
Gastric glands in the fundic region of the stomach (4)
Mucous neck cells
Chief cells
Parietal cells
Endocrine cells
What do mucous neck cells secrete
Mucus
What do chief cells produce
Pepsinogen
What do parietal cells produce
Hydrochloric acid
What do endocrine cells produce
Gastrin
Pyloric region of stomach
Produces mucus
Compartments to rumen stomach
Rumen
Reticulum
Omasum
Abomasum
Rumen
Largest portion
Fermentation
Reticulum
‘Hardware compartment’
Most cranial portion, not separate from rumen
Honeycomb
Passageway for food, paces contractions of rumen
Usually where foreign bodies are found
Omasum
Grinds up food
Absorbs water & bicarbonate
Many layers of laminae
Abomasum
‘True stomach’
Site of chemical digestion
Regions of small intestine (3)
Duodenum
Jejunum
Ileum
What structures increase surface area of small intestine
Microvilli
Circular folds
Intestinal villi
Digestive enzymes (3)
Lipase
Amylase
Lipase
Portions of the large intestine
Cecum
Colon
Function of large intestine
Water absorption
Vitamin B & K production
Propel digesta towards rectum
What vitamins are produced in the large intestine
B
K
What does the pancreas produce in the digestive process
Sodium bicarbonate
Roll of sodium bicarbonate during digestion
Neutralizes acidic chyme and digestive enzymes in the duodenum
Trypsin
Digests proteins
Lipase
Digest fat
Amylase
Digests starch
Function of liver in digestion
Produce bile
Roll of bile in digestion
Emulsifies fat
Toll of gallbladder in digestive system
Stores and releases bile when fat is present
What animals do not have a gallbladder
Rats
Horses
What substance controls release of bile
Cholecystokinin (CCK)
Pancreatic Enzymes (7)
Pancreatic amylase Trypsin Chymotrypsin Elastase Peptidase Lipase Nuclease
Pancreatic amylase
Act on starch
Chymotrypsin
Acts on proteins
Elastase
Acts on elastin
Peptidases
Act on large peptides / proteins
Nucleases
Act on nucleic acids
Small intestine enzymes (5)
Trypsin Maltase Sucrase Lactase Nuclease
Functions of lymph system (4)
Absorb protein containing fluid from capillaries and returns to venous system
Transport fat from digestive tract to blood
Produce lymphocytes
Develop immunity
Lymph organs (4)
Spleen
Tonsils
Thymus
Mucosa-associated lymphatic tissue (MALT)
Spleen as lymph tissue
Largest mass of lymph tissue
Phagocytic
Lymphocyte production
Storage & release of blood
Tonsils as lymph tissue
Embedded in mucous membrrane
Supplied with reticuloendothelial cells
Thymus location
Cranial chest, between trachea & ribs
What is the thymus responsible for
Developing immune response in young
What happens to the thymus as a patient ages
Turns to fat
Mucosa associated lymphatic tissue (MALT)
Found in mucosal lining throughout the body
Parts of the respiratory system (8)
Nostrils / nares Nasal cavity Pharynx Larynx Trachea Bronchi Bronchiole Lungs
3 step process to respiration
Ventilation
External respiration
Internal respiration
Ventilation
Movement of air between atmosphere and lungs
External respiration
Exchange of gases between alveoli and blood
Internal respiraton
Exchange of gases between blood and cells
Physiologic process to inhalation
Nervous impulse from brain
Diaphragm & external intercostal muscles contract
Decrease of intrathoracic pressure
Physiologic process to exhalation
Diaphragm & external intercostal muscles relax
Increase of intrathoracic pressure
Passive process
Tidal volume
Volume of air exchanged during normal breathing
Inspiratory reserve volume
Amount of air inspired over the tidal volume
Expiratory reserve volume
Amount of air expired over the tidal volume
Residual volume
Air remaining in the lungs after a forced expiration
Dead space (respiratory)
Air in the pathways of the respiratory system
Dog RR
16-32
Cat RR
20-42
Horse RR
8-16
Cow RR
12-36
Pig RR
32-58
Sheep RR
32-58
Llama RR
12-30
Mouse RR
80-230
Hering-Breuer reflex
Stretch receptors in the lungs that prevent lungs from overinflating
Factors affecting respiration rate
Carbon dioxide pH Pain Cold Blood pressure Oxygen Stress
Pneumothorax
Air in the thoracic cavity
Atelectasis
Collapsed lungs
Pleuritis / Pleurisy
Inflammation of the pleural membranes
Pneumonia
Inflammation of the lungs caused by bacteria, virus or chemical irritant
Eupnea
Normal, quiet respiration
Dyspnea
Difficult breathing
Apnea
No breathing
Components of outer cortex of the kidney (4)
Glomerulus
Bowman capsule
Proximal convoluted tubules
Distal convoluted tubules
3 phases to urine production
Filtration
Reabsorption
Secretion
Antidiuretic Hormone
Vasopressin
Increases reabsorption of water in kidney
Aldosterone
Stimulates sodium reabsorption in kidney
Where is sperm produced
Seminiferous tubules
Where is testosterone produced
Interstitial cells of Leydig
Where is sperm matured and stored
Seminiferous tubules
Histologic layers of female reproductive tract (3)
Endometrium
Myometrium
Perimetrium
Monestrous
One estrus cycle per year
Seasonal breeders
Diestrous
Cycle in spring and fall
Polyestrous
More than 1 cycle per year
Seasonally polyestrous
Cycle continuously in specific seasons
Reflex / Induced Ovulation
Ovulation occurs only after breeding / stimulation
Spontaneous Ovulation
Ovulation occurs regardless of breeding
Stages of estrous cycle (5)
Proestrus Estrus Metestrus Diestrus Anestrus
Proestrus
Preparation & attraction
Follicular growth
Estrus
‘Standing heat’
Luteinizing hormone produces ovulation
Metestrus
Postovulatory phase
CL forms in place of ruptured follicle
Progesterone production
Diestrus
CL degeneration if no pregnancy
CL continues if pregnant
Anestrus
Long period of inactivity in seasonally polyestrus animals
Fetal membranes (3)
Amnion
Allantois
Chorion
Amnion
Fluid filled sac closes to fetus, filled with amniotic fluid
Allantois
Two-layered membrane, one layer adheres to amnion, other layer adheres to chorion
Chorion
Outermost layer of fetal membrane, attaches to endometrium
Cat & Dog gestation
63 days
Horse gestation
336 days
Cow gestation
285 days
Pig gestation
114 days
Sheep gestation
147 days
Goat gestation
150 days
Contents of collostrum
Antibodies
Proteins
Vitamins
Roll of prolactin
Milk production
Where is prolactin produced
Pituitary
What influences milk letdown
Oxytocin
Where is oxytocin produced
Hypothalamus
Where is oxytocin released from
Pituitary gland
How is hormone secretion most commonly regulated
Negative feedback
What controls the adrenal medulla secretory function
Neural control
Thyroxin action
Accelerates metabolism
Calcitonin action
Regulates calcium levels
Parathormone action
Regulates calcium and phosphorus levels
Layers of the skin
Epidermis
Dermis / Corium
Hypodermis
Sclera
Outermost fibrous layer of the eye
White of the eye
Uvea
Middle vascular layer of the eye
Consists of the iris, ciliary body, and choroid
Tapetum lucidum
In most domestic animals
Highly reflective
Ciliary body (eye)
Supports lens, major site for production of aqueous humor
Choroid
Vascular coat between sclera and retina
Retina
Outermost layer of the eye, light sensitive, houses photoreceptors
Vitreous humor
Clear gel occupying space between lens and retina
Lens
Focuses light on retina
Aqueous humor
Clear watery fluid filling anterior and posterior chambers between the lens and cornea
Cornea
Transparent covering on the eye
Three regions of the ear
Outer ear
Middle ear
Inner ear
Outer ear
Pinna up to and including tympanic membrane
Middle ear
Houses ossicles, communicates with nasopharynx
Ossicles (3)
Malleus / hammer
Incus / anvil
Stapes / stirrup
Inner ear
Fluid filled
Houses cochlea, vestibule, semicircular canals
Cochlea
Houses hearing receptors / organ of Corti
Nerve Deafness
Malfunction of receptors or auditory nerve
Transmission Deafness
Malfunction in transmission of soundwaves from outer ear to inner ear