Anatomy and Surgery 1 Flashcards
Lining of epidermis
Stratified squamous epithelium
Immune cells in the epidermis
Langerhan’s cells
Nerve cells in dermis
Meissner’s (light touch), Pacinian (pressure)
Major chemoattractant for fibroblasts during the proliferation phase of wound healing
PDGF
Threshold of pressure injury
At least 1 hour of 60mmHg pressure
Apocrine gland blockage, infection and abscess formation
Hidradenitis suppurativa
Present as nodules and spread to form draining tracts. (+) sulfur granules on histology
Actinomycosis - follows tooth extraction, osontogenic infection, facial trauma
Rapidly enlarging, necrotic ulcer with violet border and surrounding erythematous halo
Pyoderma gangrenosum - linked to ulcerative colitis, IBD
Immune mediated, separation of skin at dermo-epidermal junction and >30% TBSA involvement
Toxic Epidermal Necrolysis
Most common site of dermoid cyst
Eyebrow
Skin lesions that yellow, non-tender, pruritic with a velvety greasy texture. Found in chest, back and abdomen,
Seborrheic keratoses - unrelated to sun exposure
Sudden multiple eruptions of seborrheic keratoses associated with ovarian or gastric Ca
Lesser Trelat Sign
Tender, warty, brown or black lesions on sun exposed areas
Solar (actinic) keratoses - premalignant (SCC)
Treatment for congenital nevi
Excision, since it is premalignant
Most common benign head and neck tumor in adults
Hemangioma - initial rapid proliferation followed by slow involution
Consumptive coagulopathy due to a hemangioma
Kasabach Merritt Syndrome
Benign neoplasm usually affecting hands
Glomus tumor - blue, subungual discolortion associated with tenderness and cold sensitivity
Most common soft tissue tumor
Lipoma
Neural tumor that invades striated skeletal muscles
Granular Cell Tumor
Histology: Neurilemoma
Schwann cells packed in palisading rows
Most common type of skin cancer?
Basal Cell Carcinoma - waxy, cream colored with rolled, pearly borders surrounding a central ulcer
Histopath: Squamous cell carcinoma
Keratin pearls
SCC in situ
Bowen’s Disease
SCC in penis
Erythroplasia of Queyrat