Anatomy and histology of lymphoid organs

Question 1

spleen filters

Answer 1

blood not lymph

Question 2

What are 4 key features of the spleen

Answer 2

• capsule
• trabeculae
• red pulp
  -white pulp

Question 3

what is the job of trabeculae

Answer 3

provide structural support for arteries and veins

Question 4

what do red pulp contain

Answer 4

splenic cords and venous sinuses

Question 5

what do white pulp contain

Answer 5

centrail arteriole, PALS, lymphatic nodules

Question 6

PALS contains

Answer 6

T- cells

Question 7

Lymphatic nodules/ follicles contain

Answer 7

B-cells

Question 8

what is the job of splenic sinuses

Answer 8

vessels that filter and circulate the blood

Question 9

some lymphoid nodules have

Answer 9

germinal center

Question 10

what is the germinal center surrounded by

Answer 10

mantle zone

Question 11

what is the mantle zone surrounded by

Answer 11

Marginal zone

Question 12

B cells actively differentiate in the

Answer 12

germinal center

Question 13

main purpose of thymus

Answer 13

T-cell proliferation and maturation

Question 14

what are removed from the thymus

Answer 14

self-reactive

Question 15

What is the origin of the thymus

Answer 15

3rd pharyngeal pouch

Question 16

….cortex, …. medulla

Answer 16

Dark: Lighter

Question 17

what does the thymus medulla do

Answer 17

produce hormones essential for t-cells

Question 18

what are hassalls corpuscles

Answer 18

degenerated epithelial cells

Question 19

what happends to the thymus with age

Answer 19

decreases in size

Question 20

when is the thymus most active and when is its peak

Answer 20

childhood: puberty

Question 21

Lymph nodes undergo

Answer 21

antigen-dependent proliferation into effector lymphocytes and memory cells

Question 22

what is the structure of lymph nodes

Answer 22

Look at the picture on slide 32

Question 23

what are the features of the lymph nodes

Answer 23

-capsule
- subcapsular sinus
- lymphoid follicles
- paracortex

Question 24

what is the outer portion of the lymp node

Answer 24

cortex

Question 25

where are most T- cells located

Answer 25

paracortex

Question 26

what does the medulla contain

Answer 26

medullary cords and sinuses

Question 27

reactive lymph nodes has

Answer 27

germinal centers with B - cells

Question 28

what is the function of Mucosa- associated lymphoid tissue ( MALT)

Answer 28

diffuse lymphatic tissue or nodules in the muscosa

Question 29

spleen chart:

capsules
cortex/medulla
cord and sinuses
b cell main region
t cell main region

Answer 29

• thick capsule
  -none ( red and white pulp)
• splenic cords and venous sinuses
  -splenic nodules ( white pulp)
• PALS

Question 30

Thymus chart:
capsules
cortex/medulla
cord and sinuses
b cell main region
t cell main region

Answer 30

• thin
• w/o lymphatic nodules/ hassall corpuscles
• No
• cortex and medulla

Question 31

Lymph nodes chart:
capsules
cortex/medulla
cord and sinuses
b cell main region
t cell main region

Answer 31

• thin
• cortex, paracortex, medulla
• medullary cords and medullary sinuses
• primary and secondary follicles
• paracortex

Question 32

Tonsil chart:
capsules
cortex/medulla
cord and sinuses
b cell main region
t cell main region

Answer 32

• incomplete epithelium and capsule
• No
• No
• Primary and Secondary follicles
• outside of the follicles