Anatomy Flashcards
Which are the two main arteries for blood supply to brain?
Internal carotid and Vertebral
Where do the internal carotid arteries begin?
Bifurcation of common carotid at C4
What arteries does internal carotid give rise to?
Ophthalmic
Posterior communicating
Anterior choroidal
Anterior cerebral
What does internal carotid become?
Middle cerebral to supply lateral cerebrum
What arteries do the vertebral arteries give rise to?
Meningeal branch to supply falx cerebelli
Ant/Post spinal
PICA
What do the vertebral arteries converge to form?
Basilar
Where do the vertebral arteries arise from?
Subclavian
What is the blood brain barrier?
Selectively permeable membrane to regulate molecules passing from blood to CNS
What makes up the BBB to make it effective?
Tight junctions in endothelial cells
No fenestrations in basement membrane
Pericytes wrap around endothelial cells and regulate cap flow, immunity and permeability
Astrocyte end feet restrict molecule flow
What percentage do internal carotid and vertebral supply to brain?
IC- 80%
Vertebral- 20%
Where does anterior cerebral supply?
Anteromedial aspects of brain
Where does posterior cerebral supply?
Posterior part of brain
Where does middle cerebral supply?
Majority of lateral brain
Which arteries supply the spine?
Anterior spinal
2x posterior spinal
Purpose of dural venous sinuses?
Drain blood from brain into jugular vein
What are the unpaired DVS?
Superior and inferior sagittal
Straight
Occipital
What are the paired DVS?
Transverse
Sigmoid
Petrosals
Cavernous
Pathway of CSF flow
Choroid plexus
Lateral ventricles
3rd ventricle via interventricular foramen
4th ventricle via cerebral aqueduct
Spinal cord or subarachnoid cisterns
What lines the choroid plexus?
Ependymal cells
What are the functions of CSF?
Protection
Buoyancy
Keeps environment chemically stable
Which notch is in the superior border of the manubrium?
Jugular
What articulates with what at the sternoclavicular joint?
Manubrium and clavicle
Which ribs articulate with the sternal body?
2-7
Which rib articulates with the xiphoid process?
7
What joint articulates rib to costal cartilage?
costochondral
What joint articulates ribs to sternum?
sternocostal
Which ribs are the true ribs?
1-7
Which ribs are the false ribs?
8-10
Which ribs are the floating ribs?
11-12
What is the joint where ribs articulate posteriorly with thoracic vertebrae?
costovertebral
How are adjacent ribs connected?
intercostal muscles
Which ribs are typical?
3-9
What are the features of typical ribs?
Head
Neck
Tubercle
Body
Which ribs are atypical?
1
2
10
11
12
Which part of the rib articulates with the vertebral body?
Head
Which part of the rib articulates with the transverse process?
Tubercle
What forms the boundary of the superior thoracic aperture?
Manubrium, first ribs and first T vertebra
What is the superior thoracic aperture?
Passageway for structures between neck and thorax
What is a dermatome?
Area of skin innervated by a single spinal nerve
Which dermatome is belly button in?
T10
Which part of breast tissue extends towards axilla?
Axillary tail
Why can’t you study the breast tissue in female cadavers?
Atrophies after menopause
What does the breast contain?
Fat
Glandular/ secretory tissue
Ducts
Areola (pigmented area)
Connective tissue and ligaments
Blood vessels and lymphatics
What is the arterial supply to the breast?
Internal thoracic (gives rise to anterior intercostals) and axillary arteries
Which nerves supply the breast?
Somatic and sympathetic fibres via intercostal nerves
Where does majority of lymph from breast drain?
Axillary lymph nodes
What are the 5 groups of lymph nodes in the axilla?
Central
Pectoral
Humeral
Subscapular
Apical
What drains into the axillary lymph nodes?
Breast
Upper limb
Chest wall
Scapulary region
Abdominal wall
Which of the 5 axilla nodes receives lymph from the other 4?
Apical
What are the 3 layers of muscles in the intercostal space?
External intercostal
Internal intercostal
Innermost intercostal
Where does pectoralis major attach?
The most superficial muscle of anterior chest wall
Attaches to the upper humerus, clavicle and upper 6 ribs
Where does pectoralis minor attach and where is it found?
Deep to pec major
Attaches to scapula and ribs 3-5
Where does serratus anterior attach and where is it found?
Found around lateral aspect of T cage
Attaches to scapula and ribs 1-8
What are the accessory muscles of breathing?
Pec major and minor
Serratus anterior
How are the external intercostal muscles orientated?
Antero-inferiorly
When is ext intercostal most active?
Inspiration as pulls the ribs superiorly
When is internal intercostal most active?
Expiration as pulls the ribs inferiorly
How do internal intercostal muscles run?
Perpendicular to external
Postero-inferior
Where is the endothoracic fascia found?
Deep to innermost intercostal and superficial to parietal pleura
Where is the neurovascular bundle in each intercostal space?
Between internal and innermost intercostal
Along inferior border of the rib superior to the space in a shallow groove
In the neurovascular bundle for the intercostal spaces which arteries are present?
Anterior intercostal from internal thoracic
Posterior intercostal from descending aorta
Where do the anterior and posterior intercostal veins drain?
Anterior: internal thoracic vein
Posterior: Azygos system
What are the intercostal nerves and what do they innervate?
Somatic
Contain motor, sensory and sympathetic
Innervate intercostal muscles, skin of chest wall and parietal pleura
What does the parietal pleura line?
Inside of thorax
What does the visceral pleura cover?
Surface of lungs and extends into fissures
What are the 4 parts of the parietal pleura?
Cervical (covers apex)
Costal (adjacent to ribs)
Mediastinal (adjacent to heart)
Diaphragmatic (adjacent to diaphragm)
What are the costodiaphragmatic and costomediastinal recesses?
Potential spaces for the lungs to expand into during deep inspiration
What innervates the parietal pleura and what does its pain feel like?
Intercostal nerves
Conscious and painful
What innervates the visceral pleura and what does the pain feel like?
Autonomic sensory nerves (visceral afferents)
Doesn’t reach conscious perception
How many lobes in the right lung and what are they?
3
Superior, middle, inferior
How many lobes in the left lung and what are they?
2
Superior + lingula (over heart), inferior
What does the oblique fissure separate in the lungs?
L: superior and inferior lobes
R: superior and middle from the inferior
What does the horizontal fissure in the right lung separate?
Superior from middle lobes
What enters the lungs at the hilum?
Pulmonary artery, veins and main bronchus
Where is the main bronchus in relation to the PA at the R and L hila?
L hilum: inferior to PA
R hilum: posterior to PA
PV usually most anterior and inferior vessels
At what level does the trachea bifurcate?
Sternal angle
How does the bronchial tree divide?
Main bronchus
Lobar bronchi (2-3)
Segmental bronchi (10) supplying a bronchopulmonary segment
Bronchioles
What is in the walls of the trachea and bronchi?
Smooth muscle and cartilage
What is in the walls of bronchioles?
Smooth muscle
Which arteries supply the lungs?
Bronchial + PA
Where do bronchial veins drain?
Azygos system
What do parasympathetic nerves in the lungs stimulate?
Bronchoconstriction
Gland secretion
What do sympathetic fibres in the lungs stimulate?
Bronchodilation
Inhibit secretion from glands
Where does lymph from the lungs drain?
Venous system via thoracic duct or R lymphatic duct
Surface anatomy markings of inferior border of lungs
6th rib anteriorly
8th rib laterally
10th rib posteriorly
Surface anatomy markings of parietal pleura
8th rib anteriorly
10th rib laterally
12th rib posteriorly
Surface anatomy of the oblique fissure
4th rib posteriorly to 6th costal cartilage anteriorly
Surface anatomy of the horizontal fissure
R
4th costal cartilage
Intersects oblique
What is the diaphragm?
A broad thin domed sheet of skeletal muscle
Central tendon in middle is fibrous
Separates thoracic and abdominal cavities
Has openings for structures to pass through
Integral to breathing
What is the diaphragm attached to?
Xiphoid process
Costal margin
Lumbar vertebrae
What happens to diaphragm during inspiration?
Contracts
Domes flatten as muscles pulled to peripheral attachments
Increases intrathoracic volume
What happens to diaphragm during expiration?
Relaxes and domes
Decreases intrathoracic volume
Pushes air from lungs
What innervates the diaphragm?
Phrenic nerves from C3,4,5
Motor and sensory
What does pleural fluid do?
Increase surface tension between parietal pleura and visceral pleura
This keeps the walls together so lungs change volume with cavities
What are the accessory muscles in breathing?
Pecs
Serratus anterior
Sternocleidomastoid
What does the mediastinum contain?
All thoracic viscera except lungs
What is found in the mediastinum?
Heart and pericardium
Great vessels
Trachea and main bronchi
Oesophagus
Nerves
Lymphatics
Veins that drain chest wall
Thymus gland
Where is the anterior mediastinum?
Posterior to sternum
Anterior to pericardial sac
Contains thymus gland in kids
What does the middle mediastinum contain?
Heart inside the pericardial sac
Pulmonary trunk
Ascending aorta
Where is the posterior mediastinum?
Between posterior aspect of pericardial sac and vertebrae
What does the superior mediastinum contain?
Arch of aorta
SVC
Trachea and oesphagus
Phrenic and vagus nerves
Thoracic duct
Thymus gland
What does the ascending aorta give rise to?
Coronary arteries to supply myocardium
What are the branches of the aortic arch?
Brachiocephalic trunk bifurcates into RCC and R subclavian
LCC
L subclavian
What do the R and L common carotid supply?
Head, neck, brain
When in the aorta are aortic bodies and chemoreceptors?
Aortic arch
How do chemoreceptors in aorta bring information back to CNS?
Vagus nerve
What is ligamentum arteriosum?
Fibrous cord connection between pulmonary trunk and aortic arch
Remnants of the ductus arteriosus
In the foetus what does the ductus arteriosus do?
Diverts blood entering pulmonary trunk to aortic arch
Closes when baby uses lungs at birth
What does the SVC do?
Returns blood from head, neck and upper limbs
What forms the SVC?
R and L brachiocephalic veins
What forms the brachiocephalic veins?
Internal jugular and subclavian
Where does the trachea terminate?
Sternal angle
T4-5
How do phrenic nerves enter the thorax?
Superior thoracic aperture
Where does the L recurrent laryngeal nerve run?
Loops under aortic arch then ascends back up alongside trachea
Where does the R recurrent laryngeal nerve run?
Descends down anterior R subclavian artery
Loops under artery then ascends between trachea and oesophagus
What does the vagus nerve give parasymp fibres to?
Heart, lungs and oesophagus
Most of abdominal viscera
Where does the thoracic duct empty?
Venous system at union of L internal jugular vein and L subclavian vein
What is the pericardium?
Tough, fibrous sac that encloses the heart
Has a visceral and parietal layer, with pericardial cavity in the middle
Innervated by branches of phrenic
Which surface of the heart is the L atrium?
Posterior
Which surface of the heart is the L and part of R ventricle?
Inferior
Which surface of the heart is the R ventricle?
Anterior
Where is the left ventricle of heart?
L pulmonary surface
Where is the R atrium on the heart?
R pulmonary surface
Surface landmarks of R border of heart
R 3rd costal cortilage to 6th
Surface landmarks of the L border of heart
L 2nd to 5th intercostal space in midclavicular line
What is a tuberosity?
large rounded projection
What is a crest?
narrow ridge of bone, usually prominent
What is a trochanter?
very large, blunt, irregularly shaped process
What is a tubercle?
small rounded projection or process
What is a foramen?
round or oval opening through bone
What is a meatus?
Canal
What is a fossa?
shallow, basinlike depression in a bone
What do the coronary arteries arise from?
Ascending aorta
Where do cardiac veins return blood to?
Coronary sinus which enters R atrium
What do the RCA and its branches supply?
Parts of conducting system
R atrium and ventricle
Part of L ventricle
Part of interventricular septum
What are the main branches of the RCA?
Branches to SAN and AVN supplying conducting system
R marginal artery supplying inferior border
Posterior interventricular artery
Where does the posterior interventricular artery run and supply?
Continuation of RCA
Runs in the posterior IV sulcus on inferior diaphragmatic surface
Supplies both ventricles
What does the LCA supply?
Parts of the conducting system
L atrium
Most of L ventricle
Part of R ventricle
Part of interventricular septum
What is the part of the LCA called before it divides?
Left main stem
What are the 2 large terminal branches of the LCA?
LAD (anterior interventricular artery)
Circumflex
What do the main branches of the LCA supply?
LAD: anterior interventricular sulcus towards apex supplying both Ventricles
Circumflex: onto inferior surface supplying L atrium, part of R ventricle and L ventricle
L marginal: from circumflex, supplies L ventricle
What determines dominance in the heart?
Whether the posterior interventricular artery arises from L or R coronary artery
Most R dominant
What does R dominance mean in the heart?
PIV arises from RCA
Both R and LCAs supply the L ventricle
What does L dominance in the heart mean?
PIV arises from circumflex
LCA supplies the entire L ventricle
So an occlusion of L main stem would cut off entire L ventricle
What do valves inside the heart ensure?
Unidirectional flow of blood through chambers of heart
What does the R atrium receive?
Deoxygenated blood from body via SVC/IVC
Deoxygenated blood from heart via coronary sinus
What does the interatrial septum separate?
R and L atria
In the R atrium
What is the fossa ovalis?
A depression in the interatrial septum
Remnant of foramen ovale
In the R atrium
What is the foramen ovale?
In foetus shunts oxygenated blood from the right atrium to the left, bypassing lungs
What is the crista terminalis?
A muscular ridge that separates the smooth walled posterior part of atrium from the anterior part (ridged wall)
Parts of the R atrium on either side have different embryological structures
What and where are the pectinate muscles in the heart?
parallel muscular columns that are present on the inner wall of the right and left atria
What valve separates R atrium and ventricle?
R atrioventricular
Tricuspid
What does the R ventricle do?
Pump deoxygenated blood into pulmonary trunk
Where is the pulmonary valve?
At entrance to pulmonary trunk to stop backflow of blood into R ventricle
What are some internal features of the R ventricle?
Interventricualr septum
Trabeculae carneae
Papillary muscles
Chordae tendinae
Moderator band
What does the interventricular septum separate?
The ventricles of heart
What are trabeculae carneae?
Muscular ridges on internal ventricle wall
What do the papillary muscles of the heart do?
attach to the cusps of the atrioventricular valves via the chordae tendineae and contract to prevent inversion or prolapse of these valves on systole
What are chordae tendineae?
Fibrous cords which connect tips of the papillary muscles to the AV valves in the ventricles
What does the moderator band in the ventricles do?
Connects interventricular septum to one of the papillary muscles
What does the L atrium receive?
Oxygenated blood from lungs via 4 pulmonary veins
What valve separates L atrium and ventricle?
Mitral
Where is the aortic valve?
At entrance to the aorta
Prevents backflow
How do the papillary muscles influence the AV valves?
Allow closed valves to resist pressure
Pressure in ventricles rises, valves close passively
Ventricles contract, papillary muscles also contract and tense the cords
Pull on valves and stop them from everting into atria
Which are the semilunar valves?
Aortic and pulmonary
Which valves in the heart are tricuspid?
All but mitral
What rate does the SAN generate impulses?
70 per minute
What do the left and right bundle branches give rise to?
Purkinje fibres
What supplies the SAN?
RCA in 60% of people
LCA in 40%
What supplies the AVN?
Posterior interventricular artery
What supplies the bundle of His?
LCA
Where can referred pain from the heart be felt?
Chest
L side of neck and arm
What does the posterior mediastinum contain?
Descending aorta
Azygos veins
Oesophagus
Thoracic duct
Symp trunk and splanchnic nerves
Posterior intercostal vessels and nerves
What are the branches of the descending aorta?
Posterior intercostal - supply intercostal spaces
Bronchial - supply lungs
Oesophageal - supply oesophagus
Pericardial branches - supply pericardium
Phrenic - supply diaphragm
At what level does the aorta pass through the diaphragm?
T12
At what level does the azygos system of veins arise?
L1/L2 in abdomen
What does the azygos system of veins drain?
Posterior thoracic wall to SVC
Posterior intercostals
Oesophageal
Bronchial
Where are the azygos veins?
In the body of T vertebrae
What does the azygos venous system comprise of?
Azygos vein on R side of vertebral bodies
Smaller hemiazygos vein on L side
One or more connecting veins
What is the arterial supply to the oesophagus?
Oesophageal arteries
At what level is the oesophageal hiatus in the diaphragm?
T10
Where does the thoracic duct lie?
Between azygos vein and aorta
What does the thoracic duct do?
Drains most of body’s lymph to venous system
Where does lymph from lower limbs, pelvis and abdomen go?
Cisterna chyli which gives rise to thoracic duct
Where does the thoracic duct terminate?
Empties into the venous system at junction between internal jugular and subclavian
What does the thoracic duct drain upper body?
Intercostal spaces and lymph nodes
L head and neck
L upper limb
What is a ganglion?
Collection of cell bodies outside the CNS
What are the abdominopelvic splanchnic nerves?
Greater and lesser splanchnic
Least splanchnic
Lumbar splanchnic
Where does the greater splanchnic nerve originate from?
T5-9
Where does the lesser splanchnic nerve originate from?
T10-T11
Where does the least splanchnic nerve originate from?
T12
Where do the lumbar splanchnic nerves originate from?
L1-2
Where are the greater, lesser and least splanchnic nerves formed?
Posterior mediastinum
What does the posterior intercostal space contain?
Intercostal muscles
A posterior intercostal artery, vein and nerve
Vein drains into azygos
What innervates the thoracic viscera?
Cardiopulmonary splanchnic convey postganglionic sympathetic fibres to the thoracic viscera
Vagus conveys parasymp
Together these form autonomic plexuses
What autonomic plexuses are found in the thorax?
Cardiac plexus
Pulmonary plexus
Oesophageal plexus
What does the cardiac plexus innervate?
SAN
Does heart rate