Analgesia And Antiemetics Flashcards
True or false, paracetamol is both analgesic and anntipyretic?
True
What is the mechanism of NSAIDs?
They block the cyclooxygenase (COX) enzyme.
What’s the adult dose if paracetamol?
1g up to 4 times a day.
What are some adverse effects of NSAIDs?
Gastrointestinal bleeding, renal damage and fluid retention.
What’s the daily dose of ibuprofen for adults?
400mg up to 3 times a day.
What is the mechanism of opiods?
They activate opioid receptors, mimicking the actions of opioid peptides.
What are some adverse reactions to opioid use?
Nausea and vomiting, constipation, drowsiness and confusion.
What is most clinically concerning in opioid overdose?
Respiratory Depression.
What are the contra indications of morphine?
Children under 1, respiratory depression, head trauma.
When must morphine be used with caution?
Pregnancy, renal/liver impairment, respiratory problems.
What is the max dose of IV morphine?
20mg
What is the antidote to opioid overdose?
Naloxone.
How can naloxone be administered?
Intranasal, intravenous and intramuscular.
What is the mechanism of metoclopramide?
It’s a dopamine receptor Antagonist.
What’s the IV dose of metoclopramide?
10mg
What is ondansetron?
Serotonin receptor Antagonist.
